34328-31-9

Basic information

• Product Name: (4-chlorophenyl)(4-(trifluoroMethyl)phenyl)Methanone
• Synonyms: (4-chlorophenyl)(4-(trifluoroMethyl)phenyl)Methanone
• CAS NO: 34328-31-9
• Molecular Formula: C₁₄H₈ClF₃O
• Molecular Weight: 284.6609296
• Mol File: 34328-31-9.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4-chlorophenyl)(4-(trifluoroMethyl)phenyl)Methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chlorophenyl)(4-(trifluoroMethyl)phenyl)Methanone(34328-31-9)
• EPA Substance Registry System: (4-chlorophenyl)(4-(trifluoroMethyl)phenyl)Methanone(34328-31-9)

Safety Data

• Hazardous Substances Data: 34328-31-9(Hazardous Substances Data)

Usage

General Description

"(4-chlorophenyl)(4-(trifluoroMethyl)phenyl)Methanone" is a chemical compound with the molecular formula C15H9ClF3O. It is a ketone derivative that consists of a 4-chlorophenyl group and a 4-trifluoromethylphenyl group attached to a central methanone group. (4-chlorophenyl)(4-(trifluoroMethyl)phenyl)Methanone is used in organic synthesis and pharmaceutical research as a building block for the synthesis of other organic compounds. It has potential applications in the development of new drugs and agrochemicals due to its unique molecular structure and properties. Additionally, it is important to handle this compound with care, as it may pose health and environmental hazards if not properly managed.

Upstream product

• 106-39-8 bromochlorobenzene 
• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 122-01-0 4-chloro-benzoyl chloride 
• 790-41-0 4-chlorobenzoic anhydride 
• 349-95-1 4-(trifluoromethyl)benzylic alcohol 
• 402-49-3 4-bromomethyltrifluoromethylbenzene 
• 1679-18-1 4-Chlorophenylboronic acid 
• 329-15-7 4-trifluoromethyl-phenyl acetyl chloride 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 104-88-1 4-chlorobenzaldehyde 
• 637-87-6 1-Chloro-4-iodobenzene 
• 199620-14-9 chromium⁽⁰⁾ hexacarbonyl 
• 455-24-3 4-trifluoromethylbenzoic acid 

Downstream Products

• 108394-93-0 (4-trifluoromethylphenyl)(4-chlorophenyl)pyrimidin-5-yl methanol 
• 1374583-66-0 (4-chlorophenyl)(4-trifluoromethylphenyl)pyridin-3-yl methanol 

Relevant articles and documents

Binuclear Palladium Complex Immobilized on Mesoporous SBA-16: Efficient Heterogeneous Catalyst for the Carbonylative Suzuki Coupling Reaction of Aryl Iodides and Arylboronic Acids Using Cr(CO)6 as Carbonyl Source

Abstract: In this study, a binuclear palladium complex immobilized on the organo-functionalized SBA-16 was prepared and structurally characterized by routine techniques. Characterizations indicated that the mesostructure of SBA-16 was maintained after the immobilization of palladium complex. Then, the prepared nanomaterial was applied as a heterogeneous catalyst in the carbonylative Suzuki coupling reaction of aryl iodides with arylboronic acids using Cr(CO)6 as carbonyl source. The catalyst was efficiently promoted the coupling reactions of various aryl iodides and arylboronic acids to give the corresponding diaryl ketones in excellent yields. Moreover, the catalyst was readily recovered by filtration and could be reused for seven cycles without losing its structural integrity and catalytic activity. Graphic Abstract: [Figure not available: see fulltext.].

Photo-nickel dual catalytic benzoylation of aryl bromides

The dual catalytic arylation of aromatic aldehydes by aryl bromides using UV-irradiation and a nickel catalyst is reported. The reaction product serves as a photocatalyst and a hydrogen atom transfer agent for this transformation.

Base free Suzuki acylation reactions of sodium (aryl trihydroxyborate) salts: A novel synthesis of substituted aryl ketones

The first simple and efficient base free Pd(PPh3)4 catalysed synthesis of substituted aryl ketones from acyl chlorides and easily accessible sodium aryl trihydroxyborate salts in aqueous toluene is reported. The reaction conditions appeared versatile and tolerable to a variety of functional groups including, CF3, OMe, SMe, Br, NO2, F, OH and NH2 furnishing 25 examples of substituted aryl ketones in isolated yields of up to 96% in 24 h. Beside the high purity, the ease and convenience of the isolation compared to boronic acids, sodium aryl trihydroxyborate salts could be used subsequently without the addition of excess amount of an activator and are more user-friendly in terms of the use of accurate reaction stoichiometry.