343317-08-8

Basic information

• Product Name: 8-Azabicyclo[3.2.1]octane-1,3-diol, 8-methyl-, (1R,3S,5R)-rel- (9CI)
• Synonyms: 8-Azabicyclo[3.2.1]octane-1,3-diol, 8-methyl-, (1R,3S,5R)-rel- (9CI)
• CAS NO: 343317-08-8
• Molecular Formula: C8H15NO2
• Molecular Weight: 157.2102
• Product Categories: ALCOHOL
• Mol File: 343317-08-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-Azabicyclo[3.2.1]octane-1,3-diol, 8-methyl-, (1R,3S,5R)-rel- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Azabicyclo[3.2.1]octane-1,3-diol, 8-methyl-, (1R,3S,5R)-rel- (9CI)(343317-08-8)
• EPA Substance Registry System: 8-Azabicyclo[3.2.1]octane-1,3-diol, 8-methyl-, (1R,3S,5R)-rel- (9CI)(343317-08-8)

Safety Data

• Hazardous Substances Data: 343317-08-8(Hazardous Substances Data)

Upstream product

• 173425-93-9 (1S,3S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-8-methyl-8-aza-bicyclo[3.2.1]oct-6-ene 
• 138-12-5 scopalamine 
• 22150-33-0 (1R,3S,5S)-3'-hydroxy-2'-phenylpropionic acid 8-methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl ester 
• 20513-09-1 (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]oct-6-en-3-ol 

Relevant articles and documents

A Meisenheimer rearrangement approach to bridgehead hydroxylated tropane alkaloid derivatives

Thermolysis of 3-t-butyldimethylsiloxy-8-methyl-8-azabicyclo[3.2.1]oct-6-ene N-oxide (11) and (12) in butyronitrile gave 3-t-butyldimethylsiloxy-9-methyl-8-oxa-9-azabicyclo[3.2.2]non-6-ene (13) which upon reductive N-O ring cleavage, hydrogenation, oxidation and deprotection yielded the 3-hydroxy analogue 8-methyl-8-azabicyclo[3.2.1]octane-1,3-diol (6a ? 6b) of the tropane alkaloid physoperuvine.