34334-24-2Relevant articles and documents
The synthesis and biological evaluation of nucleobases/tetrazole hybrid compounds: A new class of phosphodiesterase type 3 (PDE3) inhibitors
Shekouhy, Mohsen,Karimian, Somaye,Moaddeli, Ali,Faghih, Zeinab,Delshad, Yousef,Khalafi-Nezhad, Ali
, (2020)
Spired by the chemical structure of Cilostazol, a selective phosphodiesterase 3A (PDE3A) inhibitor, several novel hybrid compounds of nucleobases (uracil, 6-azauracil, 2-thiuracil, adenine, guanine, theophylline and theobromine) and tetrazole were designe
gem-Dithioacetylated indole derivatives as novel antileishmanial agents
Porwal, Sharad,Gupta, Suman,Chauhan, Prem M.S.
, p. 4643 - 4646 (2017/09/29)
In this communication we report a serendipitously discovered hybrid molecule 1, combining fragment of 3 (an in vivo active antileishmanial molecule) with H2S donor moiety (known for bimodal behavior of cytoprotection and apoptosis), as antileis
Design and synthesis of amidino-tyrosine derivatives as non-peptide fibrinogen receptor antagonists
Xu, Tian-Lin,Jiang, Xun-Tian,Hua, Wei-Yi,Ni, Pei-Zhou,Pei, Yong-Mei
, p. 1933 - 1936 (2007/10/03)
The design, synthesis and antiaggregation activity of amidino-tyrosine derivatives based on Arg-Gly-Asp (RGD) tripepride sequence as non-peptide fibrinogen receptor antagonists is described. Optimization of the spacer and the substituent at the C-terminal is reported.