3436-04-2

Basic information

• Product Name: 5-(3-bromopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene
• Synonyms: 5-(3-bromopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene;AKOS AKM00336;5-(3-BROMO-PROPYLIDENE)-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTENE(WXG02096)
• CAS NO: 3436-04-2
• Molecular Formula: C₁₈H₁₇Br
• Molecular Weight: 313.23
• Mol File: 3436-04-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(3-bromopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-bromopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene(3436-04-2)
• EPA Substance Registry System: 5-(3-bromopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene(3436-04-2)

Safety Data

• Hazardous Substances Data: 3436-04-2(Hazardous Substances Data)

Upstream product

• 14341-93-6 5-Hydroxy-5-(3-hydroxy-propyl)-10,11-dihydro-5H-dibenzocyclohepten 
• 1210-35-1 10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-one 
• 54314-84-0 1-[(3-bromopropoxy)methyl]-benzene 
• 14493-36-8 5-Hydroxy-5-<3-hydroxy-propinyl>-10,11-dihydro-5H-dibenzocyclohepten 
• 3241-97-2 5-cyclopropyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ol 

Downstream Products

• 16235-12-4 5-<3-(N-Methyl-p-toluolsulfonamido)-propyliden>-10,11-dihydro-dibenzocyclohepten 
• 72-69-5 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine 
• 1210-35-1 10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-one 
• 1423077-90-0 N-(3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)propyl)-4-cyanobenzenesulfonamide 
• 1423077-91-1 N-(3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)propyl)-4-fluorobenzenesulfonamide 
• 1423077-69-3 4-chloro-N-(3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)propyl)benzenesulfonamide 
• 1423077-70-6 N-(3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)propyl)-4-(trifluoromethoxy)benzenesulfonamide 

Relevant articles and documents

OLIGOMER-TRICYCLIC CONJUGATES

The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water soluble oligomer.

Synthesis and SAR study of diphenylbutylpiperidines as cell autophagy inducers

A novel series of diphenylbutylpiperidines as autophagy inducers was described and extensive SAR studies resulted in derivatives (15d-e, 15i-j) with 10-fold greater activity than the lead compounds 1 and 2. Meanwhile, a new synthetic route to diphenylbutyl bromide (6) from bromobenzene and γ-butyrolactone was also reported here.

N-substituted azaheterocyclic carboxylic acids and esters thereof

The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.