344-48-9

Basic information

• Product Name: 4,4'-OXYBIS[3-(TRIFLUOROMETHYL)BENZENAMINE]
• Synonyms: 4,4'-OXYBIS[3-(TRIFLUOROMETHYL)BENZENAMINE];2,2'-Bis(trifluoromethyl)-4,4'-diaminodiphenyl ether;4,4'-Oxybis(3-(trifluoroMethyl)aniline);BenzenaMine,4,4'-oxybis[3-(trifluoroMethyl)-;2,2'-Bis(trifluoromethyl)-4,4'-diaminodiphenyl ether(6FODA);4,4'-OXYBIS[3-(TRIFLUOROMETHYL)BENZEMINE];Bis(trifluoromethyl)-4,4'-diaminodiphenyl ether (6FODA);2,2'-Bis(trifluoromethyl)-4,4'-diaminediphenyl Ether
• CAS NO: 344-48-9
• Molecular Formula: C₁₄H₁₀F₆N₂O
• Molecular Weight: 336.2324192
• Mol File: 344-48-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 365.7±42.0 °C(Predicted)
• Appearance: /
• Density: 1.451±0.06 g/cm3(Predicted)
• PKA: 4.15±0.10(Predicted)
• CAS DataBase Reference: 4,4'-OXYBIS[3-(TRIFLUOROMETHYL)BENZENAMINE](CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-OXYBIS[3-(TRIFLUOROMETHYL)BENZENAMINE](344-48-9)
• EPA Substance Registry System: 4,4'-OXYBIS[3-(TRIFLUOROMETHYL)BENZENAMINE](344-48-9)

Safety Data

• Hazardous Substances Data: 344-48-9(Hazardous Substances Data)

Usage

Description

4,4'-OXYBIS[3-(TRIFLUOROMETHYL)BENZENAMINE], also known as 2,2'-bis(trifluoromethyl)-4,4'-diaminodiphenyl ether (CAS# 344-48-9), is an ether derivative with the molecular formula C15H12F6N2O. It is a useful research chemical compound, primarily utilized as an intermediate in organic synthesis due to its unique structural properties and reactivity.

Uses

Used in Chemical Synthesis:
4,4'-OXYBIS[3-(TRIFLUOROMETHYL)BENZENAMINE] is used as a synthetic intermediate for the production of various complex organic compounds. Its trifluoromethyl and benzenamine groups provide unique reactivity and functional group compatibility, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4,4'-OXYBIS[3-(TRIFLUOROMETHYL)BENZENAMINE] is used as a key intermediate in the development of novel drug candidates. Its unique structure allows for the creation of molecules with specific biological activities, targeting various therapeutic areas such as oncology, cardiovascular diseases, and neurological disorders.
Used in Material Science:
4,4'-OXYBIS[3-(TRIFLUOROMETHYL)BENZENAMINE] also finds application in the field of material science, where it can be used to develop new materials with enhanced properties. Its incorporation into polymers and other materials can lead to improved thermal stability, chemical resistance, and mechanical strength.
Used in Research and Development:
As a research chemical, 4,4'-OXYBIS[3-(TRIFLUOROMETHYL)BENZENAMINE] is employed in various academic and industrial research laboratories. It serves as a starting material or a tool compound for exploring new reaction pathways, understanding structure-activity relationships, and developing innovative synthetic methodologies.

Upstream product

• 344-47-8 4,4'-dinitro-2,2'-bistrifluoromethyldiphenyl ether 
• 777-37-7 4-chloro-3-(trifluoromethyl)nitrobenzene 

Relevant articles and documents

Fluorinated N,N-bis-imides

This invention relates to novel fluorinated N,N-bis-imides of the formula STR1 wherein R is a bivalent radical of the formula STR2 The compounds are particularly useful as monomers in the preparation of high performance polymer.