34405-42-0 Usage
Description
2-AMINO-2-METHYL-1-PHENYL-PROPAN-1-OL, also known as β-Hydroxyl Phentermine, is a compound derived from 2-Nitropropane (N519600). It is characterized by its ability to induce oxidative stress and has been identified as a carcinogen. This organic compound has unique properties that make it a subject of interest in various scientific and medical applications.
Uses
Used in Pharmaceutical Research:
2-AMINO-2-METHYL-1-PHENYL-PROPAN-1-OL is used as a research compound for its role in inducing DNA polymerase β-dependent base excision repair in response to oxidative stress in the liver. This application is significant for understanding the mechanisms of cellular response to oxidative damage and potentially developing treatments for related conditions.
Used in Toxicology Studies:
As a known carcinogen, 2-AMINO-2-METHYL-1-PHENYL-PROPAN-1-OL is utilized in toxicology studies to investigate the effects of carcinogens on biological systems. This helps in the development of preventive measures and treatments for cancer and other diseases associated with oxidative stress.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-AMINO-2-METHYL-1-PHENYL-PROPAN-1-OL may serve as a starting material or intermediate for the production of other pharmaceuticals or chemical compounds with various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 34405-42-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,4,0 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 34405-42:
(7*3)+(6*4)+(5*4)+(4*0)+(3*5)+(2*4)+(1*2)=90
90 % 10 = 0
So 34405-42-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H15NO/c1-10(2,11)9(12)8-6-4-3-5-7-8/h3-7,9,12H,11H2,1-2H3
34405-42-0Relevant articles and documents
Benzenesulfonyl-Asymmetric Ureas and Medical Uses Thereof
-
Paragraph 0198; 0200, (2017/10/10)
Benzenesulfonyl-asymmetric ureas are provided for the treatment of conditions modulated by the ghrelin receptor.
Electrochemical Reduction of Tertiary Nitroalkanes to Amines
Ohmori, Hidenobu,Furusako, Shoji,Kashu, Mieko,Ueda, Chihiro,Masui, Masaichiro
, p. 3345 - 3353 (2007/10/02)
Electrochemical reduction of tertiary nitroalkanes, 2-substituted-1,1-dimethyl-1-nitroethanes (1), was investigated in aqueous buffer solutions.In polarography, 1 with a phenyl group and/or a hydroxyl group at the 2-position showed an ill-defined wave in the weakly acidic and neutral pH region at relatively high negative potentials, in addition to a well-defined wave arising from the reduction of 1 to the corresponding hydroxylamine (2).Controlled potential electrolysis of 1 at the potential of the former wave gave the 1,1-dimethylethylamines (3) as well as the hydroxylamines 2.The amines 3 are formed exclusively from 2, probably via the O-protonated form.It is suggested that a phenyl group at the 2-position facilitates the reduction of 2 to 3 by enhancing the adsorption of 2 at the mercury cathode and that a hydroxyl group, while it interferes with the adsorption, assists the reduction by intramolecular hydrogen-bonding to stabilize the O-protonated form of 2.Keywords - tertiary nitroalkane; alkylhydroxylamine; electrochemical reduction; polarography; controlled potential electrolysis.
A New Synthesis of β-Aminoalcohols via O-Silylated Cyanohydrins
Amouroux, Roger,Axiotis, Georges P.
, p. 270 - 272 (2007/10/02)
-
