344307-16-0

Basic information

• Product Name: 4-Hydroxy-1-phenyl-1,3-dihydro-indol-2-one
• CAS NO: 344307-16-0
• Molecular Weight: 225.247
• Mol File: 344307-16-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Hydroxy-1-phenyl-1,3-dihydro-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hydroxy-1-phenyl-1,3-dihydro-indol-2-one(344307-16-0)
• EPA Substance Registry System: 4-Hydroxy-1-phenyl-1,3-dihydro-indol-2-one(344307-16-0)

Safety Data

• Hazardous Substances Data: 344307-16-0(Hazardous Substances Data)

Upstream product

• 536-90-3 m-Anisidine 
• 101-16-6 3-methoxy-N-phenylaniline 
• 591-50-4 iodobenzene 
• 64053-59-4 N-chloroacetyl-N-phenyl-m-anisidine 

Downstream Products

• 83254-80-2 4-Methoxy-1-phenyl-1,3-dihydro-indol-2-one 

Relevant articles and documents

MONO(m-SUBSTITUTED) CHLOROACETYLDIARYLAMINES IN THE STOLLE REACTION

The effect of substituted (OCH3, Cl) on the ratio of the isomeric N-aryloxindoles formed in the Stolle reaction from mono(m-substituted) chloroacetyldiarylamines was studied.It was shown by means of gas-liquid chromatography (GLC) and PMR spectroscopy that in the case of the methoxy group electrophilic substitution occurs only in the ring activated by the substituent.The presence of a halogen atom leads only to 1-(m-chlorophenyl)oxindole.The results show that high selectivity of the attack by the carbonium ion on the phenyl rings with electron-donor and electron-acceptor substituents is also retained in the case of intramolecular electrophilic substitution under conditions of kinetic control.