345-55-1

Basic information

• Product Name: 1-[2'-fluoro(1,1'-biphenyl)-4-yl]ethan-1-one
• Synonyms: 1-[2'-fluoro(1,1'-biphenyl)-4-yl]ethan-1-one;4'-(o-Fluorophenyl)acetophenone
• CAS NO: 345-55-1
• Molecular Formula: C₁₄H₁₁FO
• Molecular Weight: 214.2349432
• EINECS: 206-461-6
• Mol File: 345-55-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 319.3°Cat760mmHg
• Flash Point: 131.5°C
• Appearance: /
• Density: 1.124g/cm³
• CAS DataBase Reference: 1-[2'-fluoro(1,1'-biphenyl)-4-yl]ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2'-fluoro(1,1'-biphenyl)-4-yl]ethan-1-one(345-55-1)
• EPA Substance Registry System: 1-[2'-fluoro(1,1'-biphenyl)-4-yl]ethan-1-one(345-55-1)

Safety Data

• Hazardous Substances Data: 345-55-1(Hazardous Substances Data)

Usage

Type of compound

Ketone

Structural feature

Fluorine-substituted biphenyl group

Potential applications

a. Organic synthesis
b. Pharmaceutical research

Usage

Building block in the synthesis of various organic molecules and pharmaceutical drugs

Research status

Further research needed to fully understand its potential uses and applications in various fields.

Upstream product

• 321-60-8 2-fluorobiphenyl 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 1993-03-9 o-fluorophenylboronic acid 
• 99-90-1 para-bromoacetophenone 

Downstream Products

• 4501-39-7 1-cyclohexyl-4-ethylbenzene 
• 365-12-8 2'-fluorobiphenyl-4-carboxylic acid 

Relevant articles and documents

Polyvinylpyridine, a versatile solid phase for coordinative immobilisation of palladium precatalysts - Applications in Suzuki-Miyaura reactions

The immobilisation of an oxime-based palladacycle on polyvinylpyridine (PVP) resin affords a reusable, air, moisture and thermally stable palladium precatalyst which exerts high activity in Suzuki-Miyaura reactions both in batch as well as continuous-flow processes. Evidence is presented which shows that, besides serving as an anchor for the precatalyst, PVP also acts as a scavenger for Pd particles present in solution. Georg Thieme Verlag Stuttgart.

Isoxazole derivatives

An isoxazole derivative represented by the formula: or a pharmaceutically acceptable salt thereof useful as a therapeutic drug for auto-immune diseases and inflammatory diseases.