34510-96-8

Basic information

• Product Name: DIETHYLISOBUTYLPHOSPHONATE
• Synonyms: DIETHYLISOBUTYLPHOSPHONATE;DIETHYL 2-BUTYLPHOSPHONATE;Butanephosphonic acid diethyl ester;Diethyl 2-butylphosphonate,98%;2-diethoxyphosphorylbutane
• CAS NO: 34510-96-8
• Molecular Formula: C8H19O3P
• Molecular Weight: 194.21
• Mol File: 34510-96-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 232.68°C (estimate)
• Flash Point: 113.1°C
• Appearance: /
• Density: 0.9800 (estimate)
• Vapor Pressure: 0.0597mmHg at 25°C
• Refractive Index: 1.4279
• CAS DataBase Reference: DIETHYLISOBUTYLPHOSPHONATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYLISOBUTYLPHOSPHONATE(34510-96-8)
• EPA Substance Registry System: DIETHYLISOBUTYLPHOSPHONATE(34510-96-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• Hazardous Substances Data: 34510-96-8(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless liquid

InChI:InChI=1/C8H19O3P/c1-5-8(4)12(9,10-6-2)11-7-3/h8H,5-7H2,1-4H3/t8-/m1/s1

Upstream product

• 108230-17-7 (1-Methyl-1-trimethylsilanyl-propyl)-phosphonic acid diethyl ester 
• 91210-98-9 C₇H₁₆LiO₃P 
• 74-88-4 methyl iodide 
• 78-38-6 ethylphosphonic acid diethyl ester 
• 57415-84-6 α-trimethylsilylvinylphosphonic acid diethyl ester 
• 66194-68-1 S-(+)-methanesulfonic acid sec-butyl ester 
• 762-04-9 phosphonic acid diethyl ester 
• 50599-13-8 S-(+)-2-butanol methanesulfonate 
• 78-76-2 s-butyl bromide 
• 122-52-1 triethyl phosphite 

Relevant articles and documents

Amberlyst-15 catalyzed synthesis of alkyl/aryl/heterocyclic phosphonates

A novel and efficient procedure for the synthesis of alkyl phosphonates through one pot condensation of alkyl halide and tri alkyl/aryl phosphite in the presence of amberlyst-15 as catalyst under solvent free conditions was applied. It demonstrated several advantages such as good yields of products, simple operation, convenient separation and inexpensive catalyst.

Phosphate-phosphonate conversion: a versatile route to linear or branched alkylphosphonates

Addition of a symmetrically substituted trialkyl phosphate (R1O)3P(O) to a THF solution of an alkyllithium R2-CH2Li (2 equiv) at -78 deg C, followed by warming to room temperature, results in the quantitative formation of α-lithioalkylphosphonate.Treatment of the anion formed with aqueous HCl or an alkyl iodide yields the corresponding alkylphosphonate or α-substituted alkylphosphonate in good to excellent yields.Key Words: trialkyl phosphonates; alkyllithiums; α-lithioalkylphosphonates; alkylphosphonates.

CONVERSION DIRECTE PAR LES ALKYLLTHIENS DES PHOSPHATES EN PHOSPHONATES α-LITHIES

Trialkylphosphates (RO)3P(O) can be converted into α-lithioalkanephosphonates by treatment with alkyllithiums (R1CH2Li) in two fold excess.