3457-48-5

Basic information

• Product Name: 4,4'-DIMETHYLBENZIL
• Synonyms: 1,2-Bis(4-methylphenyl)-1,2-ethanedione;1,2-Di-p-tolyl-ethane-1,2-dione;di-p-tolylethanedione;Ethanedione, bis(4-methylphenyl)-;Ethanedione,bis(4-methylphenyl)-;LABOTEST-BB LT00159323;4,4'-DIMETHYLDIBENZOYL;4,4'-DIMETHYLBENZIL
• CAS NO: 3457-48-5
• Molecular Formula: C₁₆H₁₄O₂
• Molecular Weight: 238.28
• EINECS: 222-388-2
• Product Categories: Aromatic Ketones (substituted);Benzil and Benzoin Compounds;Organic Photoinitiators;Polymerization Initiators
• Mol File: 3457-48-5.mol
• Article Data: 170

Chemical Properties

• Melting Point: 102-104 °C(lit.)
• Boiling Point: 211 °C (7 mmHg)
• Flash Point: 168.6 °C
• Appearance: yellow crystals or needles
• Density: 1.119±0.06 g/cm3 (20 ºC 760 Torr)
• Refractive Index: 1.6290 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4,4'-DIMETHYLBENZIL(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-DIMETHYLBENZIL(3457-48-5)
• EPA Substance Registry System: 4,4'-DIMETHYLBENZIL(3457-48-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-36/37-26
• WGK Germany: 3
• Hazardous Substances Data: 3457-48-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 95, p. 1296, 1973 DOI: 10.1021/ja00785a047Tetrahedron Letters, 34, p. 3897, 1993 DOI: 10.1016/S0040-4039(00)79257-4

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 99-94-5 p-Toluic acid 
• 79-37-8 oxalyl dichloride 
• 108-88-3 toluene 
• 460-19-5 ethanedinitrile 
• 2789-88-0 1,2-bis(4-methylphenyl)acetylene 
• 1218-89-9 4,4'-dimethylbenzoin 
• 99-75-2 4-methyl-benzoic acid methyl ester 
• 4528-66-9 bis(4-methylphenyl)-acetaldehyde 
• 40030-78-2 4,4'-dimethylbenzil monohydrazone 
• 201230-82-2 carbon monoxide 
• 6293-68-1 bis(4-methylphenyl)iodonium bromide 
• 4342-61-4 1,2-dichlorotetramethylsilane 
• 874-60-2 4-methyl-benzoyl chloride 

Downstream Products

• 2216-49-1 triphenylmethyl radical 
• 1218-89-9 4,4'-dimethylbenzoin 
• 92405-78-2 5,6-bis(p-methylphenyl)-2,3-dihydropyrazine 
• 62497-27-2 3,4-bis(4-methylphenyl)thiophene-2,5-dicarboxylic acid 
• 40030-85-1 bis-(4,4'-dimethyl-α'-oxo-bibenzyl-α-ylidene)-hydrazine 
• 858007-60-0 4,4'-dimethyl-benzil-dihydrazone 
• 2695-79-6 bis-p-tolylhydroxyacetic acid 
• 5173-28-4 (1R,2S)-1,2-Di-p-tolyl-ethane-1,2-diol 
• 5314-79-4 α,α'-bis-benzoyloxy-4,4'-dimethyl-stilbene 
• 16112-18-8 2,4,5-tri(4-methylphenyl)-1,3-oxazole 
• 99-94-5 p-Toluic acid 
• 22985-87-1 meso-2,3-bis(4-methylphenyl)-2,3-butanediol 
• 22985-88-2 dl-2,3-bis(4-methylphenyl)-2,3-butanediol 
• 40030-78-2 4,4'-dimethylbenzil monohydrazone 

Relevant articles and documents

Electrochemical oxidation-induced benzyl C–H carbonylation for the synthesis of aromatic α-diketones

Electrochemical oxidation-induced direct carbonylation of benzyl C–H bond for the synthesis of aromatic α-diketones is described. In this process, tetrabutylammonium iodide (nBu4NI) not only acts as an electrolyte, but its iodine anion is oxidized to an iodine radical at the anode, acting as a hydrogen atom transfer agent. The iodine radical extracts the benzyl hydrogen atom and causes the carbonylation of the benzyl position, where O2 in the air is used as an oxygen source.

One-pot cascade synthesis of α-diketones from aldehydes and ketones in water by using a bifunctional iron nanocomposite catalyst

A new methodology for the synthesis of α-diketones was reportedviaa one-pot cascade process from aldehydes and ketones catalyzed by a bifunctional iron nanocomposite using H2O2as a green oxidant in water. The one-pot strategy showed excellent catalytic stability, comprehensive suitability of substrates and important practical utility for directly synthesizing biologically active and medicinally valuable N-heterocyclesviaan intermittent process.

One-pot synthesis, structural analysis, and oxidation applications of a series of diaryltellurium dicarboxylates

This paper presents a concise and efficient one-pot synthesis of a variety of functionalized diaryltellurium dicarboxylates. The method is based on a mild photosensitized oxygenation of cheap and readily available carboxylic acids. The molecular structures of the diaryltellurium dicarboxylates were determined unambiguously using single-crystal X-ray diffraction analysis. The thus obtained diaryltellurium dicarboxylates were used to study the oxidation of benzoin derivatives.