34574-69-1 Usage
Description
3-Hydroxy-dodecanedioic acid, also known as azelaic acid, is a naturally occurring dicarboxylic acid found in various human tissues and fluids. It is a nine-carbon dicarboxylic acid with a hydroxyl group at the third carbon, exhibiting both acidic and hydroxyl functionalities. This unique structure allows it to interact with various biological systems and molecules, making it a versatile compound with potential applications in different fields.
Uses
Used in Pharmaceutical Applications:
3-Hydroxy-dodecanedioic acid is used as a therapeutic agent for treating various skin conditions, particularly acne and rosacea. It exhibits anti-inflammatory and antimicrobial properties, which help reduce inflammation, redness, and the presence of harmful bacteria on the skin. Additionally, it has been shown to reduce the appearance of hyperpigmentation, making it a valuable component in skincare products.
Used in Metabolic Disorder Research:
3-Hydroxy-dodecanedioic acid is used as a research tool for studying fatty acid metabolic disorders such as ketoacidosis. In these conditions, enzyme deficiencies are believed to be present, and the study of azelaic acid can help researchers understand the underlying mechanisms and potential treatment strategies for these disorders.
Used in Industrial Applications:
3-Hydroxy-dodecanedioic acid is used as a building block for the synthesis of various chemicals, including polymers, surfactants, and lubricants. Its unique structure allows it to be incorporated into a wide range of materials, providing specific properties and functionalities that can be tailored for different applications.
Check Digit Verification of cas no
The CAS Registry Mumber 34574-69-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,5,7 and 4 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 34574-69:
(7*3)+(6*4)+(5*5)+(4*7)+(3*4)+(2*6)+(1*9)=131
131 % 10 = 1
So 34574-69-1 is a valid CAS Registry Number.
34574-69-1Relevant articles and documents
Enzymatic Oxidative Tandem Decarboxylation of Dioic Acids to Terminal Dienes
Dennig, Alexander,Kurakin, Sara,Kuhn, Miriam,Dordic, Andela,Hall, Mélanie,Faber, Kurt
supporting information, p. 3473 - 3477 (2016/07/29)
The biocatalytic oxidative tandem decarboxylation of C7–C18dicarboxylic acids to terminal C5–C16dienes was catalyzed by the P450 monooxygenase OleT with conversions up to 29 % for 1,11-dodecadiene (0.49 g L–1). The sequential nature of the cascade was proven by the fact that decarboxylation of intermediate C6–C11ω-alkenoic acids and heptanedioic acid exclusively gave nonconjugated 1,4-pentadiene; scale-up allowed the isolation of 1,15-hexadecadiene and 1,11-dodecadiene; the system represents a short and green route to terminal dienes from renewable dicarboxylic acids.
