34582-09-7

Basic information

• Product Name: 1-bromo-2-(tert-butyl)-4,5-dimethoxybenzene
• Synonyms: 1-bromo-2-(tert-butyl)-4,5-dimethoxybenzene
• CAS NO: 34582-09-7
• Molecular Weight: 273.17
• Mol File: 34582-09-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-bromo-2-(tert-butyl)-4,5-dimethoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-2-(tert-butyl)-4,5-dimethoxybenzene(34582-09-7)
• EPA Substance Registry System: 1-bromo-2-(tert-butyl)-4,5-dimethoxybenzene(34582-09-7)

Safety Data

• Hazardous Substances Data: 34582-09-7(Hazardous Substances Data)

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 41280-64-2 4-(tert-butyl)-1,2-dimethoxybenzene 

Relevant articles and documents

Synthesis of Amides and Esters by Palladium(0)-Catalyzed Carbonylative C(sp3)?H Activation

The 1,4-palladium shift strategy allows the functionalization of remote C?H bonds that are difficult to reach directly. Reported here is a domino reaction proceeding by C(sp3)?H activation, 1,4-palladium shift, and amino- or alkoxycarbonylation, which generates a variety of amides and esters bearing a quaternary β-carbon atom. Mechanistic studies showed that the aminocarbonylation of the σ-alkylpalladium intermediate arising from the palladium shift is fast using PPh3 as the ligand, and leads to the amide rather than the previously reported indanone product.

6-alkyl derivatives of 3-(3,4-dihydroxyphenyl)alanine (Dopa). I. Synthesis via oxazolinones.

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