34611-07-9

Basic information

• Product Name: 2,2-DIPHENYLPROPAN-1-AMINE HYDROCHLORIDE
• Synonyms: Propylamine,2,2-diphenyl- (6CI,8CI); 2,2-Diphenylpropan-1-amine; 2,2-Diphenylpropylamine
• CAS NO: 34611-07-9
• Molecular Formula: C₁₅H₁₇N
• Molecular Weight: 0
• Mol File: 34611-07-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 328.1°Cat760mmHg
• Flash Point: 152.7°C
• Appearance: /
• Density: 1.023g/cm³
• CAS DataBase Reference: 2,2-DIPHENYLPROPAN-1-AMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIPHENYLPROPAN-1-AMINE HYDROCHLORIDE(34611-07-9)
• EPA Substance Registry System: 2,2-DIPHENYLPROPAN-1-AMINE HYDROCHLORIDE(34611-07-9)

Safety Data

• Hazardous Substances Data: 34611-07-9(Hazardous Substances Data)

Upstream product

• 5558-67-8 2,2-diphenylpropionitrile 
• 86-29-3 Diphenylacetonitrile 

Downstream Products

• 98383-65-4 N₆-(2,2-Diphenylpropyl)-2-aminoadenosine 
• 90530-64-6 2,2'-[(2,2-Diphenylpropyl)imino]bis[ethanol]Hydrochloride 
• 1219623-60-5 N-(2,2-diphenylpropyl)-2-(2-oxo-3,3-diphenylpyrrolidin-1-yl)acetamide 
• 1219624-46-0 2-[3,3-bis(4-fluorophenyl)-2-oxopyrrolidin-1-yl]-N-(2,2-diphenylpropyl)acetamide 
• 1219624-72-2 N-(2,2-diphenylpropyl)-2-(2-oxo-3,3-diphenylpiperidin-1-yl)acetamide 
• 37391-19-8 3-methyl-3-phenylindoline 

Relevant articles and documents

Investigation of the mechanism of decyanation of 2,2-diphenylpropionitrile induced by LiAlH4

The LiAlH4 reduction of 2,2-diphenylpropionitrile (4) in THF yields a mixture of the hycrocarbon 6 and the expected amine 5. Medium effects and reduction with LiAID4 suggest a mechanism involving the attack of the hydride reagent on the cyano carbon atom followed by the fragmentation of the formed imine salt intermediate. Copyright

Synthesis of indolines by copper-mediated intramolecular aromatic C-H amination

A Cu(OAc)2-mediated intramolecular aromatic C-H amination proceeds with the aid of a picolinamide-type bidentate coordination group to deliver the corresponding indolines in good yields. The reaction occurs smoothly even under noble-metal-free conditions, and in some cases the use of an MnO2 terminal oxidant renders the process catalytic in Cu. The mild oxidation aptitude of Cu(OAc)2 and/or MnO2 accommodates the formation of electron-rich thiophene-and indole-fused indoline analogues. The Cu-based system can provide an effective approach to various indolines of potent interest in pharmaceutical and medicinal chemistry.