3463-26-1 Usage
Description
1-methyl-3-phenyl-pyrazole is an organic compound with the molecular formula C10H10N2. It is a heterocyclic compound featuring a pyrazole ring fused with a phenyl group. 1-methyl-3-phenyl-pyrazole is known for its potential applications in various fields due to its unique chemical structure and properties.
Uses
1-methyl-3-phenyl-pyrazole is used as a research reagent for the synthesis of bioactive important small molecules. Its expression is as follows:
Used in Pharmaceutical Industry:
1-methyl-3-phenyl-pyrazole is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly those with potential therapeutic applications. Its unique structure allows for the development of new drugs with improved efficacy and selectivity.
Used in Chemical Research:
1-methyl-3-phenyl-pyrazole serves as a valuable research tool in the field of organic chemistry, enabling scientists to explore new reaction pathways and develop innovative synthetic methods. Its versatile structure makes it a promising candidate for the creation of novel chemical entities with diverse applications.
Used in Material Science:
1-methyl-3-phenyl-pyrazole may also find applications in the development of new materials with specific properties, such as those with enhanced conductivity, magnetism, or optical characteristics. Its unique structure can be exploited to design and synthesize advanced materials for various industrial applications.
Synthesis Reference(s)
The Journal of Organic Chemistry, 62, p. 8325, 1997 DOI: 10.1021/jo970897r
Check Digit Verification of cas no
The CAS Registry Mumber 3463-26-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,6 and 3 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3463-26:
(6*3)+(5*4)+(4*6)+(3*3)+(2*2)+(1*6)=81
81 % 10 = 1
So 3463-26-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H10N2/c1-12-8-7-10(11-12)9-5-3-2-4-6-9/h2-8H,1H3
3463-26-1Relevant articles and documents
Cascade reaction to 1H-pyrazoles from hydrazones via sodium Ni-trite promoted dual C–C/C–N formation, annulation and aromatization with 1,2-dichloroethane
Hao, Liqiang,Liu, Hongyan,Zhang, Zheng,Wen, Fuqiang,Xia, Chengcai,Pang, Zengfen
, p. 2309 - 2312 (2021/03/16)
A novel route for tandem C–C/C–N formation, annulation and aromatization of hydrazones with 1,2-dichloroethane to synthesize 1H-pyrazoles has been developed. Furthermore, the 1,2-dichloroethane serves as alkylation reagent in good to excellent yields. This methodology features mild reaction conditions and good functional group tolerance, providing a direct approach for the preparation of 1H-pyrazoles.
Cu-promoted sydnone cycloadditions of alkynes: Scope and mechanism studies
Comas-Barcel?3, Jffllia,Foster, Robert S.,Fiser, B??la,Gomez-Bengoa, Enrique,Harrity, Joseph P. A.
supporting information, p. 3257 - 3263 (2015/03/05)
Cu salts have been found to promote the cycloaddition reaction of sydnones and terminal alkynes, providing significant reduction in reaction times. Specifically, the use of Cu(OTf)2 is found to provide 1,3-disubstituted pyrazoles, whereas simpl
Synthesis of ynone trifluoroborates toward functionalized pyrazoles
Kirkham, James D.,Edeson, Steven J.,Harrity, Joseph P. A.,Stokes, Stephen
supporting information, p. 5354 - 5357,4 (2012/12/12)
The synthesis of a range of novel ynone trifluoroborates has been achieved, in a two-pot process from propargylic alcohols. These alkynes have been subsequently used in the formation of a range of pyrazole trifluoroborate salts via cyclization with hydrazines. The products are generated with high levels of regiocontrol and in excellent yields and represent versatile synthetic intermediates.
