34658-65-6

Basic information

• Product Name: 2,4-Imidazolidinedione, 5-phenyl-3-(phenylmethyl)-
• CAS NO: 34658-65-6
• Molecular Formula: C16H14N2O2
• Molecular Weight: 266.299
• Mol File: 34658-65-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,4-Imidazolidinedione, 5-phenyl-3-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Imidazolidinedione, 5-phenyl-3-(phenylmethyl)-(34658-65-6)
• EPA Substance Registry System: 2,4-Imidazolidinedione, 5-phenyl-3-(phenylmethyl)-(34658-65-6)

Safety Data

• Hazardous Substances Data: 34658-65-6(Hazardous Substances Data)

Upstream product

• 22003-17-4 O-phenyl N-benzylcarbamate 
• 15028-39-4 L-2-phenylglycine methyl ester hydrochloride 
• 100-52-7 benzaldehyde 
• 89-24-7 5-phenylimidazolidine-2,4-dione 
• 100-44-7 benzyl chloride 
• 3173-56-6 benzyl isothiocyanate 
• 15028-40-7 DL-2-phenylglycine methyl ester hydrochloride 
• 201230-82-2 carbon monoxide 
• 538-32-9 benzylurea 

Downstream Products

• 1443523-40-7 C₂₁H₂₂N₂O₂ 
• 1443523-41-8 C₂₁H₂₈N₂ 
• 1443523-47-4 5-(3-methylbut-2-enyl)-5-phenyl-3-phenylmethyl-2,4-imidazolidinedione 
• 85369-83-1 (4R,5R)-1-Benzyl-5-hydroxy-4-phenyl-imidazolidin-2-one 
• 85369-83-1 cis-3-benzyl-5-phenyl-4-hydroxy-2-imidazolidinone 

Relevant articles and documents

Facile One-Pot Synthesis of Substituted Hydantoins from Carbamates

A novel and simple approach for the preparation of 3-substituted, 5-substituted, or 3,5-disubstituted hydantoins is reported. It involves the reaction of α-amino methyl ester hydrochlorides with carbamates to yield the corresponding ureido derivatives, which subsequently cyclize under basic conditions to produce substituted hydantoins in good yields. By applying this method, the bioactive anticonvulsant drug ethotoin was synthesized in good yield. The process avoids conventional multistep protocols and does not use the hazardous, irritant, toxic, or moisture-sensitive reagents, such as isocyanates or chloroformates, that are commonly used for the synthesis of these important compounds.

Functionalized amino acid anticonvulsants: Synthesis and pharmacological evaluation of conformationally restricted analogues

Proven conformationally restricted analogues of anticonvulsant functionalized amino acids (FAAs) were prepared using short-range cyclizations and evaluated in pharmacological assays providing new information concerning the structural requirements for FAA function.