346665-40-5

Basic information

• Product Name: 4-(5-Nitro-pyridin-2-yloxy)-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-(5-Nitro-pyridin-2-yloxy)-piperidine-1-carboxylic acid tert-butyl ester;2-[[N-(tert-Butoxycarbonyl)-4-piperidinyl]oxy]-5-nitropyridine;tert-Butyl 4-[(5-nitropyridin-2-yl)oxy]piperidine-1-carboxylate;4-(5-Nitro-pyridin-2-yloxy)-piperidine-1-Carbocylic acid tert-butyl ester
• CAS NO: 346665-40-5
• Molecular Formula: C15H21N3O5
• Molecular Weight: 323.34434
• Mol File: 346665-40-5.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Density: 1.247
• CAS DataBase Reference: 4-(5-Nitro-pyridin-2-yloxy)-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-Nitro-pyridin-2-yloxy)-piperidine-1-carboxylic acid tert-butyl ester(346665-40-5)
• EPA Substance Registry System: 4-(5-Nitro-pyridin-2-yloxy)-piperidine-1-carboxylic acid tert-butyl ester(346665-40-5)

Safety Data

• Hazardous Substances Data: 346665-40-5(Hazardous Substances Data)

Usage

General Description

4-(5-Nitro-pyridin-2-yloxy)-piperidine-1-carboxylic acid tert-butyl ester is a chemical compound that is commonly used in pharmaceutical research and development. It is a tert-butyl ester derivative of 4-(5-Nitro-pyridin-2-yloxy)-piperidine-1-carboxylic acid, which is a potential drug candidate for the treatment of various diseases. 4-(5-Nitro-pyridin-2-yloxy)-piperidine-1-carboxylic acid tert-butyl ester has the potential to inhibit certain enzymes and receptors in the body, making it a promising candidate for drug development. Its unique structure and properties make it of interest to researchers in the field of medicinal chemistry, and it has the potential to contribute to the development of new and effective medications.

Upstream product

• 4548-45-2 2-chloro-5-nitropyridine 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 5418-51-9 5-nitro-2-hydroxypyridine 

Downstream Products

• 346665-41-6 tert-butyl 4-((5-aminopyridin-2-yl)oxy)piperidine-1-carboxylate 
• 916345-54-5 5-nitro-2-(piperidin-4-yloxy)pyridine 

Relevant articles and documents

PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY

Pyrazole compounds (I) for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a pyrazole compounds, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis Alzheimer's disease, lung disease, inflammation, auto-immune diseases and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as neurological conditions/disorders/diseases linked to overexpression of DYRK1A.

SUBSTITUTED THIOHYDANTOIN DERIVATIVES AS ANDROGEN RECEPTOR ANTAGONISTS

Disclosed are compounds, compositions and methods for treating of disorders that are affected by the antagonism of one or more androgen receptor types. Such compounds are represented by Formula (I) as follows: Formula (I) wherein R1 and G are defined herein.

NOVEL PIPERIDINE DERIVATIVE

Disclosed is a substance having an antagonistic effect on the binding of histamine to a histamine H3 receptor or an inhibitory effect on the activity which a histamine H3 receptor constantly exhibits. A compound represented by the formula (I) or a pharmac