34692-44-9 Usage
Description
[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate is a complex phosphodiester molecule consisting of two adenine units, each attached to a dihydroxyoxolan-2-yl group. These groups are linked to a methoxy-hydroxyphosphoryl and a methyl hydrogen phosphate moiety, respectively. This molecule is likely to play a role in biological processes related to the storage and transfer of genetic information, as well as in enzymatic reactions.
Uses
Used in Genetic Research:
[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate is used as a research tool for studying the mechanisms of genetic information storage and transfer, as well as the role of phosphodiester bonds in enzymatic reactions.
Used in Pharmaceutical Development:
In the pharmaceutical industry, this complex molecule may be used as a starting point for the development of new drugs targeting genetic diseases or conditions related to the malfunction of genetic information processing.
Used in Biochemical Analysis:
[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate can be employed in biochemical analysis to understand the interactions between nucleic acids and proteins, which is crucial for the development of targeted therapies and diagnostic tools.
Check Digit Verification of cas no
The CAS Registry Mumber 34692-44-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,6,9 and 2 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 34692-44:
(7*3)+(6*4)+(5*6)+(4*9)+(3*2)+(2*4)+(1*4)=129
129 % 10 = 9
So 34692-44-9 is a valid CAS Registry Number.
InChI:InChI=1/C20H26N10O15P2/c21-19-25-13-7(15(35)27-19)23-3-29(13)17-11(33)9(31)5(43-17)1-41-46(37,38)45-47(39,40)42-2-6-10(32)12(34)18(44-6)30-4-24-8-14(30)26-20(22)28-16(8)36/h3-6,9-12,17-18,31-34H,1-2H2,(H,37,38)(H,39,40)(H3,21,25,27,35)(H3,22,26,28,36)/t5-,6-,9-,10-,11-,12-,17-,18-/m1/s1
34692-44-9Relevant articles and documents
Kinetic analysis of the temperature dependence of the template-directed formation of oligoguanylate from the 5′-phosphorimidazolide of guanosine on a poly(C) template with Zn2+
Kawamura,Umehara
, p. 927 - 935 (2001)
A kinetic study of the temperature dependence of the template-directed formation of oligoguanylate (oligo(G)) on polycytidylic acid (poly(C)) from the 5′-phosphorimidazolide of guanosine (ImpG) has been carried out in the presence of Zn2+ at 40
One-Pot Synthesis of α,γ-Dinucleoside 5'-Triphosphates, G5'pppG and A5'pppA, Using S,S'-Bis(4-chlorophenyl)phosphorodithioate
Fukuoka, Koichiro,Suda, Fuminori,Suzuki, Ryo,Ishikawa, Masahide,Hata, Tsujiaki
, p. 499 - 502 (2007/10/02)
S,S'-Bis(4-chlorophenyl) phosphorodithioate was useful for the synthesis of α,γ-dinucleoside 5'-triphosphates, G5'pppG and A5'pppA starting from the corresponding unprotected nucleoside 5'-phosphates under neutral conditions. G5'pppG was used for the synthesis of m7G5'pppG by means of the N7-methylation of one of two guanine moieties of G5'pppG.
