3470-45-9

Basic information

• Product Name: 1-OXO-INDAN-5-CARBOXYLIC ACID
• Synonyms: 1-Oxoindan-5-carboxylic acid;1-oxo-2,3-dihydro-1H-indene-5-carboxylic acid;2,3-dihydro-1-oxo-1H-Indene-5-carboxylic acid;1H-INDENE-5-CARBOXYLIC ACID,2,3-DIHYDRO-1-OXO;1-Oxoindane-5-carboxylic Acid
• CAS NO: 3470-45-9
• Molecular Formula: C₁₀H₈O₃
• Molecular Weight: 176.17
• Mol File: 3470-45-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 389.1 °C at 760 mmHg
• Flash Point: 203.3 °C
• Appearance: /
• Density: 1.381 g/cm³
• Vapor Pressure: 9.46E-07mmHg at 25°C
• Refractive Index: 1.631
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.75±0.20(Predicted)
• CAS DataBase Reference: 1-OXO-INDAN-5-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-OXO-INDAN-5-CARBOXYLIC ACID(3470-45-9)
• EPA Substance Registry System: 1-OXO-INDAN-5-CARBOXYLIC ACID(3470-45-9)

Safety Data

• Hazardous Substances Data: 3470-45-9(Hazardous Substances Data)

Usage

General Description

1-OXO-INDAN-5-CARBOXYLIC ACID, also known as oxindole-5-carboxylic acid, is a chemical compound with the molecular formula C10H8O3. It is a white crystalline solid with a melting point of 228-230°C. 1-OXO-INDAN-5-CARBOXYLIC ACID is used as an intermediate in the synthesis of pharmaceuticals and dyes. Its versatile reactivity allows it to be used in the preparation of various heterocycles and biologically active compounds. It has potential applications in the pharmaceutical industry due to its ability to act as a versatile building block for the synthesis of bioactive compounds.

InChI:InChI=1/C10H8O3/c11-9-4-2-6-5-7(10(12)13)1-3-8(6)9/h1,3,5H,2,4H2,(H,12,13)

Upstream product

• 91880-84-1 1-oxo-indan-5-carboxylic acid amide 
• 25724-79-2 5-cyano-1-indanone 
• 3470-54-0 5-aminoindan-1-one 
• 59856-06-3 5-acetamidoindane 
• 34598-49-7 5-Bromo-1-indanone 
• 68634-02-6 methyl 2,3-dihydro-1-oxo-1H-indene-5-carboxylate 

Downstream Products

• 68634-02-6 methyl 2,3-dihydro-1-oxo-1H-indene-5-carboxylate 
• 1267507-95-8 N-[2-ethyl-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6-methylphenyl]-1-oxoindanecarboxamide 
• 1267507-96-9 N-[2-ethyl-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6-methylphenyl]-1-(hydroxyimino)indane-5-carboxamide 
• 1267507-26-5 tert-butyl (5-{[2-ethyl-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6-methylphenyl]carbamoyl}-2,3-dihydro-1H-inden-1-yl)carbamate 
• 1267508-13-3 1-amino-N-[2-ethyl-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6-methylphenyl]indane-5-carboxamide 
• 1267507-22-1 1-acetamide-N-[2-ethyl-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6-methylphenyl]indane-5-carboxamide 

Relevant articles and documents

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5H, 10H-IMIDAZO[1,2-A]INDENO[1,2-E] PYRAZIN-4-ONE DERIVATIVES, PREPARATION THEREOF, AND DRUGS CONTAINING SAID DERIVATIVES

Compounds of formula (I), wherein R is a hydrogen atom or a carboxy, alkoxycarbonyl,--CO--NR 4 R 5,--PO 3 H 2 or--CH 2 OH radical, and R 1 is an-alk-NH 2,-alk-NH--CO--R 3,-alk-COOR 4,-alk-CO--NR 5 R 6 or--CO--NH--R 7 radical. The compounds of formula (I) have valuable pharmacological properties and are antagonists of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor also known as the quisqualate receptor. Furthermore, the compounds of formula (I) are non-competitive antagonists of the N-methyl-D-aspartame (NMDA) receptor and more specifically are ligands for NMDA receptor glycine modulator sites.