34702-60-8

Basic information

• Product Name: BOC-L-PENTAFLUOROPHENYLALANINE
• Synonyms: (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(2,3,4,5,6-pentafluorophenyl)propanoic acid;Boc-pentafluoro-L-phenylalanine >=98.0% (HPLC);Boc-L-Pentafluoro-phe-OH;(S)-Boc-2-amino-3-(pentafluorophenyl)propionic acid;Boc-pentafluoro-L-phenylalanine≥ 99% (HPLC, Chiral purity);L-PENTAFLUOROPHENYLALANINE, BOC PROTECTED;BOC-1,2,3,4,5-PENTAFLUORO-L-PHENYLALANINE;BOC-L-PENTAFLUOROPHE
• CAS NO: 34702-60-8
• Molecular Formula: C14H14F5NO4
• Molecular Weight: 355.26
• Product Categories: Amino Acids;Phenylalanine analogs and other aromatic alpha amino acids;Amino Acid Derivatives;a-amino
• Mol File: 34702-60-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 411.1 °C at 760 mmHg
• Flash Point: 202.4 °C
• Appearance: /
• Density: 1.422 g/cm³
• Storage Temp.: -15°C
• PKA: 3.70±0.20(Predicted)
• CAS DataBase Reference: BOC-L-PENTAFLUOROPHENYLALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-L-PENTAFLUOROPHENYLALANINE(34702-60-8)
• EPA Substance Registry System: BOC-L-PENTAFLUOROPHENYLALANINE(34702-60-8)

Safety Data

• Hazard Codes: Xi
• WGK Germany: 3
• Hazardous Substances Data: 34702-60-8(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

BOC-L-Pentafluorophenylalanine is an intermediate used in the self-assembly of tripeptides into functional coating material that resists biofouling.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1207604-34-9 C₁₈H₁₇F₅N₂O₆ 

Relevant articles and documents

Incorporation of fluorinated phenylalanine generates highly specific inhibitor of proteasome's chymotrypsin-like sites

Proteasomal processing is conducted by three individual catalytic subunits, namely β11, β2, and β5. Subunit-specific inhibitors are useful tools in dissecting the role of these individual subunits and are leads toward the development of antitumor agents. We here report that the presence of fluorinated phenylalanine derivatives in peptide based proteasome inhibitors has a profound effect on inhibitor potency and selectivity. Specifically, compound 4a emerges as one of the most β5 specific inhibitors known to date.