347370-91-6

Basic information

• Product Name: (1H-benzo[d][1,2,3]triazol-1-yl)(2-hydroxyphenyl)methanone
• Synonyms: (1H-benzo[d][1,2,3]triazol-1-yl)(2-hydroxyphenyl)methanone
• CAS NO: 347370-91-6
• Molecular Weight: 239.233
• Mol File: 347370-91-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (1H-benzo[d][1,2,3]triazol-1-yl)(2-hydroxyphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (1H-benzo[d][1,2,3]triazol-1-yl)(2-hydroxyphenyl)methanone(347370-91-6)
• EPA Substance Registry System: (1H-benzo[d][1,2,3]triazol-1-yl)(2-hydroxyphenyl)methanone(347370-91-6)

Safety Data

• Hazardous Substances Data: 347370-91-6(Hazardous Substances Data)

Upstream product

• 3679-66-1 N-(2-aminophenyl)salicylamide 
• 95-14-7 1,2,3-Benzotriazole 
• 69-72-7 salicylic acid 
• 37183-26-9 salicylic acid-(2-nitro-anilide) 
• 493-53-8 sodium O-acetylsalicylate 
• 5538-51-2 O-acetylsalicyloyl chloride 

Downstream Products

• 119-36-8 methyl salicylate 
• 37592-64-6 (2S)-3-hydroxy-2-[(2-hydroxybenzoyl)amino]propanoic acid 
• 155880-02-7 (4S)-2-[2-hydroxyphenyl]-Δ²-1,3-oxazoline-4-carboxylic acid 
• 87-17-2 salicylanilide 
• 59-49-4 2-Benzoxazolinone 
• 863238-54-4 2',3'-O,O-bis(t-butyldimethylsilyl)-5'-O-(N-salicylsulfamoyl)adenosine 
• 79349-24-9 5-(2-hydroxyphenyl)-3-phenyl-1,2,4-oxadiazole 
• 144726-74-9 2-(3-(p-tolyl)-1,2,4-oxadiazol-5-yl)phenol 
• 1374754-47-8 2-(5-butyl-3-(p-tolyl)-4,5-dihydro-1,2,4-oxadiazol-5-yl)phenol 
• 13156-92-8 N-(furan-2-ylmethyl)-2-hydroxybenzamide 
• 2890-83-7 (2-hydroxyphenyl)(piperidin-1-yl)methanone 

Relevant articles and documents

Nickel-Catalyzed Reductive Cross-Coupling of N-Acyl and N-Sulfonyl Benzotriazoles with Diverse Nitro Compounds: Rapid Access to Amides and Sulfonamides

Herein we report a Ni-catalyzed reductive transamidation of conveniently available N-acyl benzotriazoles with alkyl, alkenyl, and aryl nitro compounds, which afforded various amides with good yields and a broad substrate scope. The same catalytic reaction conditions were also applicable for N-sulfonyl benzotriazoles, which could undergo smooth reductive coupling with nitroarenes and nitroalkanes to afford the corresponding sulfonamides.

An efficient one-pot synthesis of: N, N ′-disubstituted ureas and carbamates from N -acylbenzotriazoles

A facile and high-yielding one-pot synthesis of carbamates and N,N′-disubstituted symmetrical ureas from N-acylbenzotriazoles has been devised. It is believed that, the intermediate acyl-azide undergo Curtius rearrangement and in different solvents gives different products i.e. carbamates in alcohols and N,N′-disubstituted symmetrical urea in THF.

Direct synthesis of esters and amides from unprotected hydroxyaromatic and -aliphatic carboxylic acids

A facile method for the activation of hydroxy-substituted carboxylic acids using benzotriazole chemistry without prior protection of the hydroxy substituents is presented. The N-acylbenzotriazole intermediates 2a-g, 6a-d, and 9a-c have been used for high-yielding synthesis of both aliphatic (3a-1) and aromatic (7a-h, 10a-f) hydroxy carboxamides. High yields of aromatic hydroxy esters 12a-h and 13a-i were obtained using either neat alcohols in neutral microwave conditions or nucleophilic alkoxides and the intermediate N-(arylacyl)benzotriazoles. Moderate yields were obtained in the case of aliphatic hydroxy esters 11a,b and thiolesters 11e-g from the intermediates 2a-c.