347386-51-0

Basic information

• Product Name: benzyl 2-(dimethoxyphosphoryl)piperidine-1-carboxylate
• Synonyms: benzyl 2-(dimethoxyphosphoryl)piperidine-1-carboxylate
• CAS NO: 347386-51-0
• Molecular Weight: 327.317
• Mol File: 347386-51-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl 2-(dimethoxyphosphoryl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 2-(dimethoxyphosphoryl)piperidine-1-carboxylate(347386-51-0)
• EPA Substance Registry System: benzyl 2-(dimethoxyphosphoryl)piperidine-1-carboxylate(347386-51-0)

Safety Data

• Hazardous Substances Data: 347386-51-0(Hazardous Substances Data)

Upstream product

• 4043-87-2 pipecolic Acid 
• 501-53-1 benzyl chloroformate 
• 28697-07-6 N-benzyloxycarbonyl D/L-pipecolinic acid 
• 69622-67-9 benzyl 2-hydroxypiperidine-1-carboxylate 
• 121-45-9 phosphorous acid trimethyl ester 

Downstream Products

• 106647-45-4 piperidine-2-phosphonic acid 

Relevant articles and documents

Chemical conversion of cyclic α-amino acids to cyclic α-aminophosphonic acids

The oxidative decarboxylation of cyclic α-amino acids having urethane-type N-protecting groups with lead tetraacetate [Pb(OAc)4] gave 2-hydroxy derivatives, which were transformed into the corresponding α-aminophosphonic acid esters by treatment of trialkyl phosphites in the presence of Lewis acids. Deprotection and ester cleavage of the products in the usual manner afforded cyclic α-aminophosphonic acids. The convenient chemical conversion of five- and six-membered cyclic α-amino acids to the corresponding cyclic α-aminophosphonic acids has been accomplished.