347840-11-3 Usage
Description
3-CHLOROANILINE-2,4,6-D3, also known as 3-Chloro-2,4,6-trideuteroaniline, is a labeled analogue of 3-Chlorobenzenamine (C364610). It is a chemical compound that plays a significant role in the development of pharmaceuticals and therapeutic agents.
Uses
Used in Pharmaceutical Synthesis:
3-CHLOROANILINE-2,4,6-D3 is used as a key intermediate in the synthesis of pyrimidoazepine analogs. These analogs act as serotonin 5-HT2A and 5-HT2C receptor ligands, which are crucial for the treatment of obesity. 3-CHLOROANILINE-2,4,6-D3's unique properties allow for the development of targeted therapies that can help address weight management issues.
Used in COX-2 Inhibitor Synthesis:
In addition to its role in obesity treatment, 3-CHLOROANILINE-2,4,6-D3 is also utilized in the synthesis of novel COX-2 inhibitors. COX-2 inhibitors are important in the management of pain and inflammation, making this compound a valuable asset in the development of new medications for these conditions.
Overall, 3-CHLOROANILINE-2,4,6-D3 is a versatile compound with applications in various areas of pharmaceutical research and development, particularly in the synthesis of serotonin receptor ligands for obesity treatment and COX-2 inhibitors for pain and inflammation management.
Check Digit Verification of cas no
The CAS Registry Mumber 347840-11-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,7,8,4 and 0 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 347840-11:
(8*3)+(7*4)+(6*7)+(5*8)+(4*4)+(3*0)+(2*1)+(1*1)=153
153 % 10 = 3
So 347840-11-3 is a valid CAS Registry Number.
347840-11-3Relevant articles and documents
DEUTERATED CHLOROKYNURENINES FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS
-
Paragraph 00217-00219, (2017/05/02)
Described are deuterated chlorokynurenines and compositions, and their application as pharmaceuticals for the treatment of disease. Methods of modulating N-methyl-D-aspartate (NMDA) receptor activity, methods of treating disorders, including neuropsychiatric disorders such as depression, epilepsy, schizophrenia, and Huntington's Disease, and use of said deuterated chlorokynurenines are also described.
Microwave assisted synthesis of multiple labelled SR244870 a compound related to ferroquine (SSR97193)
Ilyas, Tenzeela,Davies, Polly,Mcneill, Alan,Smith, David Ian
, p. 477 - 479 (2008/02/08)
-
