348-19-6

Basic information

• Product Name: 2'-FLUORO-4'-NITROACETANILID
• Synonyms: 2'-FLUORO-4'-NITROACETANILID;2-FLUORO-4-NITRO-ACETANILIDE;2-Fluoro-4-niroacetanilide;N-(2-Fluoro-4-nitrophenyl)acetamide
• CAS NO: 348-19-6
• Molecular Formula: C₈H₇FN₂O₃
• Molecular Weight: 198.15
• Mol File: 348-19-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 200-201 °C(Solv: ethanol (64-17-5))
• Boiling Point: 391.0±32.0 °C(Predicted)
• Appearance: /
• Density: 1.429±0.06 g/cm3(Predicted)
• PKA: 12.83±0.70(Predicted)
• CAS DataBase Reference: 2'-FLUORO-4'-NITROACETANILID(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-FLUORO-4'-NITROACETANILID(348-19-6)
• EPA Substance Registry System: 2'-FLUORO-4'-NITROACETANILID(348-19-6)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 348-19-6(Hazardous Substances Data)

Usage

General Description

2'-FLUORO-4'-NITROACETANILID, also known as FNAA, is a chemical compound with the molecular formula C8H7FN2O3. It is a derivative of acetanilide and contains a fluorine and nitro group. FNAA is often used in the synthesis of pharmaceutical compounds and other organic molecules. It has been studied for its potential pharmacological properties and has shown to have analgesic and anti-inflammatory effects. Additionally, FNAA has been used in research as a building block for the development of new drugs and as a reagent in organic chemistry. However, it is important to handle FNAA with caution, as it may have toxic or hazardous properties.

Upstream product

• 399-31-5 N-(2-fluorophenyl)acetamide 
• 108-24-7 acetic anhydride 
• 104-04-1 N-(4-Nitrophenyl)acetamide 
• 348-54-9 2-Fluoroaniline 
• 369-35-7 2-fluoro-4-nitroaniline 

Downstream Products

• 369-35-7 2-fluoro-4-nitroaniline 
• 7800-26-2 2,4-dinitro-1-fluorobenzene 
• 160984-03-2 N-(4-amino-2-fluorophenyl)-1-cyclohexene-1,2-dicarboximide 
• 160984-02-1 N-(2-fluoro-4-nitrophenyl)-1-cyclohexene-1,2-dicarboximide 
• 57165-12-5 4-amino-2-fluoroacetanilide 

Relevant articles and documents

Design, synthesis and antitubercular activity of 4-alkoxy-triazoloquinolones able to inhibit the M. tuberculosis DNA gyrase

A number of new F-triazolequinolones (FTQs) and alkoxy-triazolequinolones (ATQs) were designed, synthesized and evaluated for their activity against Mycobacterium tuberculosis H37Rv. Five out of 21 compounds exhibited interesting minimum inhibitory concen

Synthesis of 2,5- and 2,6-dinitrofluorobenzenes and related hydroquinones

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Fluorination process

According to the present invention there is provided a process for the selective introduction of one or more fluorine atoms into a disubstituted aromatic compound in an acid medium with fluorine gas characterized in that the acid medium has a dielectric constant of at least 20 and a pH of less than 3. The present process provides a cost effective means of selectively introducing one or more fluorine atoms into an aromatic compound in good overall yield.