348-20-9Relevant articles and documents
USE OF KINASE INHIBITORS TO PROMOTE NEOCHONDROGENESIS
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Page/Page column 29, (2010/10/20)
This invention provides methods for utilizing compounds that inhibit cyclin-dependent kinase and tyrosine kinase enzymes in the promotion of neochondrogenesis and the enhancement, protection and repair of cartilage. In certain embodiments the invention relates to methods of using compounds of formula (I): and pharmaceutically acceptable salts thereof, to promote neochondrogenesis, wherein, R1,R2, R3, R4, R5, R6, A, B, D, and E have any of the values defined therefor in the specification.
Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues
H?gberg, Marita,Sahlberg, Christer,Engelhardt, Per,Noréen, Rolf,Kangasmets?, Jussi,Johansson, Nils Gunnar,?berg, Bo,Vrang, Lotta,Zhang, Hong,Sahlberg, Britt-Louise,Unge, Torsten,L?vgren, Seved,Fridborg, Kerstin,B?ckbro, Kristina
, p. 4150 - 4160 (2007/10/03)
The further development of allosteric HIV-1 RT inhibitors in the urea analogue series of PETT (phenylethylthiazolylthiourea) derivatives is described here. The series includes derivatives with an ethyl linker (1-5) and racemic (6-16) and enantiomeric (17-
