34849-50-8

Basic information

• Product Name: Acetic acid, (2-acetyl-4-bromophenoxy)-, ethyl ester
• CAS NO: 34849-50-8
• Molecular Formula: C12H13BrO4
• Molecular Weight: 301.137
• Mol File: 34849-50-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Acetic acid, (2-acetyl-4-bromophenoxy)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, (2-acetyl-4-bromophenoxy)-, ethyl ester(34849-50-8)
• EPA Substance Registry System: Acetic acid, (2-acetyl-4-bromophenoxy)-, ethyl ester(34849-50-8)

Safety Data

• Hazardous Substances Data: 34849-50-8(Hazardous Substances Data)

Usage

General Description

Acetic acid, (2-acetyl-4-bromophenoxy)-, ethyl ester is a chemical compound with the molecular formula C12H13BrO4. It is an ethyl ester derivative of acetic acid, containing a bromine and acetyl group attached to a phenoxy ring. Acetic acid, (2-acetyl-4-bromophenoxy)-, ethyl ester is commonly used in the synthesis of pharmaceuticals and agrochemicals, as well as in research and development. It has various industrial applications, including as an intermediate in the production of fine chemicals and as a building block in organic synthesis. Additionally, it is utilized in the formulation of adhesives, coatings, and other specialty products. However, it is important to handle this chemical with caution as it may have hazardous properties if not used properly.

Upstream product

• 105-36-2 ethyl bromoacetate 
• 1761-61-1 5-bromosalicyclaldehyde 
• 1450-75-5 5-Bromo-2-hydroxyacetophenone 
• 90-02-8 salicylaldehyde 

Downstream Products

• 1396753-10-8 3-methyl-5-(4 ,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzofuran 
• 50638-08-9 5-bromo-3-methyl-1-benzofuran-2-carboxylic acid 
• 188714-70-7 5-[2-(2-Bromo-3-bromomethyl-benzofuran-5-yl)-phenyl]-1-trityl-1H-tetrazole 
• 188714-69-4 5-[2-(3-Bromomethyl-benzofuran-5-yl)-phenyl]-1-trityl-1H-tetrazole 
• 188714-68-3 5-[2-(3-Methyl-benzofuran-5-yl)-phenyl]-1-trityl-1H-tetrazole 
• 33118-85-3 5-bromo-3-methyl-1-benzofuran 
• 34849-51-9 (2-acetyl-4-bromophenoxy)acetic acid 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS FOR THE TREATMENT OF HYPERPARATHYROIDISM, CHRONIC RENAL FAILURE AND CHRONIC KIDNEY DISEASE

The invention relates to heterocyclic compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their pharmaceutical compositions for use in medicine for the treatment of diseases or disorders associated with the modulation of calcium sensing receptor modulators (CaSR), like e.g. hyperparathyroidism, chronic renal failure and chronic kidney disease and their complications.

Preparation of 2-, 3-, 4- and 7-(2-alkylcarbamoyl-1-alkylvinyl)benzo[b] furans and their BLT1 and/or BLT2 inhibitory activities

Several 2-alkylcarbamoyl-1-alkylvinylbenzo[b]furans were designed to find a selective leukotriene B4 (LTB4) receptor antagonist. 2-(2-Alkylcarbamoyl-1-alkylvinyl)benzo[b]furans having a substituent group at the 3-position, 4-(2-alkylcarbamoyl-1-methylvinyl)benzo[b]furans having a substituent group at the 3-position, and 7-(2-alkylcarbamoyl-1-methylvinyl) benzo[b]furans and 3-(2-alkylcarbamoyl-1-alkylvinyl)benzo[b]furans were prepared and evaluated for LTB4 receptor (BLT1 and BLT 2) inhibitory activities. (E)-3-Amino-4-[2-[2-(3,4-dimethoxyphenyl) ethylcarbamoyl]-1-methylvinyl]benzo[b]furan ((E)-17c) showed potent and selective inhibitory activity for BLT2. On the other hand, (E)-7-(2-diethylcarbamoyl-1-methylvinyl)benzo[b]furan ((E)-27a) showed potent inhibitory activity for both BLT1 and BLT2. This journal is The Royal Society of Chemistry.

Biaryl sulfonamides and methods for using same

The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.