348640-10-8 Usage
Pyrrolopyridine core
The compound has a core structure consisting of a fusion of a pyrrole and a pyridine ring, which are both five-membered heterocyclic aromatic rings.
Iodine atom
The compound contains an iodine atom attached to the pyrrolopyridine core, which may influence its reactivity and properties.
Sulfonyl group
A sulfonyl group (-SO2-) is present in the compound, which is a key functional group that can affect the compound's reactivity and stability.
Methylphenyl moiety
The sulfonyl group is attached to a 4-methylphenyl group, which is a phenyl ring with a methyl substituent at the para position.
Organic synthesis
The compound may be used as a building block or intermediate in the synthesis of more complex organic molecules.
Medicinal chemistry
Due to its unique structural features, the compound may have potential applications in the development of new drugs or pharmaceutical agents.
Drug development
Further research and testing may reveal potential therapeutic uses or properties of the compound.
Specific Properties
The specific properties of 1H-Pyrrolo[2,3-b]pyridine, 2-iodo-1-[(4-methylphenyl)sulfonyl]would depend on further research and testing, as its unique structure may impart distinct chemical and physical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 348640-10-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,8,6,4 and 0 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 348640-10:
(8*3)+(7*4)+(6*8)+(5*6)+(4*4)+(3*0)+(2*1)+(1*0)=148
148 % 10 = 8
So 348640-10-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H11IN2O2S/c1-10-4-6-12(7-5-10)20(18,19)17-13(15)9-11-3-2-8-16-14(11)17/h2-9H,1H3
348640-10-8Relevant articles and documents
Design of potent IGF1-R inhibitors related to bis-azaindoles
Nemecek, Conception,Metz, William A.,Wentzler, Sylvie,Ding, Fa-Xiang,Venot, Corinne,Souaille, Catherine,Dagallier, Anne,Maignan, Sebastien,Guilloteau, Jean-Pierre,Bernard, Francois,Henry, Alain,Grapinet, Sandrine,Lesuisse, Dominique
, p. 100 - 106 (2011/03/19)
From an azaindole lead, identified in high throughput screen, a series of potent bis-azaindole inhibitors of IGF1-R have been synthesized using rational drug design and SAR based on a in silico binding mode hypothesis. Although the resulting compounds produced the expected improved potency, the model was not validated by the co-crystallization experiments with IGF1-R.
