3488-22-0

Basic information

• Product Name: but-2c-enoyl chloride
• Synonyms: but-2c-enoyl chloride
• CAS NO: 3488-22-0
• Molecular Weight: 104.536
• Mol File: 3488-22-0.mol
• Article Data: 40

Chemical Properties

• CAS DataBase Reference: but-2c-enoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: but-2c-enoyl chloride(3488-22-0)
• EPA Substance Registry System: but-2c-enoyl chloride(3488-22-0)

Safety Data

• Hazardous Substances Data: 3488-22-0(Hazardous Substances Data)

Upstream product

• 3724-65-0 2-butenoic acid 
• 107-93-7 (E)-but-2-enoic acid 
• 50966-31-9 1,1-dichloroethyl ethyl ether 
• 625-68-3 3-chlorobutyric acid 
• 190734-66-8 (E)-1-(but-2-enoyl)pyrrolidin-2-one 
• 98-88-4 benzoyl chloride 

Downstream Products

• 143470-11-5 N,N-Dimethyl-N'-cis-propenyl-harnstoff 
• 14915-01-6 (Z)-But-2-enoic acid (3S,8S,9S,10R,13R,14S,17R)-17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 
• 103023-67-2 [1-((Z)-But-2-enoyl)-pyrrolidin-(2E)-ylidene]-acetic acid ethyl ester 
• 51944-66-2 (E)-1-(4-morpholinyl)-2-buten-1-one 
• 879554-13-9 trans-crotonic acid-(3,4-dimethyl-phenyl ester) 
• 119840-33-4 trans-m-methoxyphenyl 2-butenoate 
• 97060-28-1 (E)-1-(4-bromophenyl)-3-hydroxybutan-1-one 
• 41873-74-9 p-tolyl crotonate 
• 54282-10-9 trans-crotonic acid-(2,5-dichloro-anilide) 
• 254115-08-7 (para-bromophenyl)-2-(E)-butenoate 
• 623-70-1 ethyl (E)-crotonate 
• 80445-62-1 1-(3,4-dimethyl-phenyl)-buten-(2t)-one-⁽¹⁾ 
• 109340-65-0 (E)-5-isopropyl-2-methylphenyl but-2-enoate 
• 35322-84-0 3,4,7-Trimethyl-1-indanone 

Relevant articles and documents

Quorum sensing and nf-κb inhibition of synthetic coumaperine derivatives from piper nigrum

Bacterial communication, termed Quorum Sensing (QS), is a promising target for virulence attenuation and the treatment of bacterial infections. Infections cause inflammation, a process regulated by a number of cellular factors, including the transcription Nuclear Factor kappa B (NF-κB); this factor is found to be upregulated in many inflammatory diseases, including those induced by bacterial infection. In this study, we tested 32 synthetic derivatives of coumaperine (CP), a known natural compound found in pepper (Piper nigrum), for Quorum Sensing Inhibition (QSI) and NF-κB inhibitory activities. Of the compounds tested, seven were found to have high QSI activity, three inhibited bacterial growth and five inhibited NF-κB. In addition, some of the CP compounds were active in more than one test. For example, compounds CP-286, CP-215 and CP-158 were not cytotoxic, inhibited NF-κB activation and QS but did not show antibacterial activity. CP-154 inhibited QS, decreased NF-κB activation and inhibited bacterial growth. Our results indicate that these synthetic molecules may provide a basis for further development of novel therapeutic agents against bacterial infections.

Bromo Radical-Mediated Photoredox Aldehyde Decarbonylation towards Transition-Metal-Free Hydroalkylation of Acrylamides at Room Temperature

Herein, we report a visible-light-mediated hydroalkylation reaction of alkenes using easily available aldehydes as alkyl sources via bromo radical-promoted photoredox decarbonylation. This protocol provides an alternative entry to C(sp3)?C(sp3) bond formation and features considerable advantages including mild and clean reaction conditions, obviation for transition-metal catalyst, and good functional group compatibility.

PROCESS FOR THE PREPARATION OF PIPERINE

The present application relates to a process for the preparation of piperine of high purity having low concentrations of isomeric impurities.