34883-08-4Relevant articles and documents
1,4,2-Dioxazines or N-Acyl Isoxazolidines from Organoselenium-induced Cyclisation of O-Allyl Hydroxamic Acids
Tiecco, Marcello,Testaferri, Lorenzo,Tingoli, Marco,Marini, Francesca
, p. 237 - 238 (1995)
O-Allyl hydroxamic acids easily give rise to organoselenium-induced cyclisation reactions to afford phenylseleno-substituted 1,4,2-dioxazines or N-acyl isoxazolidines as the kinetically or thermodynamically controlled products, respectively.
PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS
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Page/Page column 121, (2018/12/13)
The present invention relates to pyrimidine derivatives of formula (I) wherein (R1)n, R3, R4a, R4b, R5a, R5b and Ar1 are as described in the description and their use in the treatment of cancer by modulating an immune response comprising a reactivation of the immune system in the tumor. The invention further relates to novel benzofurane and benzothiophene derivatives of formula (II) and their use as pharmaceuticals, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.
Naturally Occuring Dibenzofurans. Part 2. The Synthesis of Schizopeltic Acid
Sargent, Melvyn V.,Stransky, Peter O.
, p. 2373 - 2378 (2007/10/02)
The structure of schizopeltic acid as 1,7-dimethoxy-8-methoxycarbonyl 3,9-dimethyldibenzofuran-4-carboxylic acid (1) has been confirmed by rational synthesis. 6-Methoxy-4-methylbenzofuran-2-carbaldehyde (10), available from 3,5-dimethoxytoluene (4) in six