349-33-7

Basic information

• Product Name: AKOS B018302
• Synonyms: 5-[(3-fluorophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one;CHEMBRDG-BB 3018302;ART-CHEM-BB B018302;AKOS B018302;(5E)-5-(3-fluorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one;Albb-009150;(5E)-5-(3-fluorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one(SALTDATA: FREE);(5Z)-5-(3-fluorobenzylidene)-2-thioxo-thiazolidin-4-one
• CAS NO: 349-33-7
• Molecular Formula: C₁₀H₆FNOS₂
• Molecular Weight: 239.29
• Mol File: 349-33-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 360.7°C at 760 mmHg
• Flash Point: 172°C
• Appearance: /
• Density: 1.5g/cm³
• Vapor Pressure: 2.17E-05mmHg at 25°C
• Refractive Index: 1.706
• Storage Temp.: 2-8°C
• CAS DataBase Reference: AKOS B018302(CAS DataBase Reference)
• NIST Chemistry Reference: AKOS B018302(349-33-7)
• EPA Substance Registry System: AKOS B018302(349-33-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 349-33-7(Hazardous Substances Data)

Usage

General Description

AKOS B018302, also known as 2-chloro-5-nitrobenzaldehyde, is a chemical compound with the molecular formula C7H4ClNO3. It is a yellow crystalline solid commonly used in the synthesis of various pharmaceuticals, agrochemicals, and dyes. AKOS B018302 is a potent antimicrobial agent and is also used as an intermediate in the manufacturing of drugs. AKOS B018302 is known for its toxic and irritating properties and should be handled with caution. It is important to follow safety guidelines and regulations when working with this chemical to prevent any harm to human health and the environment.

InChI:InChI=1/C10H6FNOS2/c11-7-3-1-2-6(4-7)5-8-9(13)12-10(14)15-8/h1-5H,(H,12,13,14)/b8-5+

Upstream product

• 141-84-4 2-thioxo-4-thiazolidinone 
• 456-48-4 3-Fluorobenzaldehyde 

Downstream Products

• 1204757-06-1 2-(2-((Z)-5-(3-fluorobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)ethyl)isoindoline-1,3-dione 
• 1544402-04-1 (Z)-5-(3-fluorobenzylidene)-2-(methylthio)thiazol-4(5H)-one 

Relevant articles and documents

A facile synthesis of (Z)-5-(substituted)-2-(methylthio)thiazol-4(5H)-one using microwave irradiation and conventional method

A new effective approach to the synthesis of some new (Z)-5-(substituted)- 2-thioxothiazolidin-4-one 3a-l and (Z)-5-(substituted)-2-(methylthio)thiazol- 4(5H)-one 5a-l is reported under microwave irradiation as well as conventional conditions.

Synthesis and characterization of (Z)-5-arylmethylidenerhodanines with photosynthesis-inhibiting properties

A series of rhodanine derivatives was prepared. The synthetic approach, analytical and spectroscopic data of all synthesized compounds are presented. Lipophilicity of all the discussed rhodanine derivatives was analyzed using the RP-HPLC method. The compo

Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2

The identification, synthesis and evaluation of a series of rhodanine and thiazolidin-2,4-dione derivatives as selective inhibitors of human arylamine N-acetyltransferase 1 and mouse arylamine N-acetyltransferase 2 is described. The most potent inhibitors