Cas 349090-90-0,N-(4-iodo-2-methylphenyl)methanesulfonamide

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Check Digit Verification of cas no

The CAS Registry Mumber 349090-90-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,9,0,9 and 0 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 349090-90:
(8*3)+(7*4)+(6*9)+(5*0)+(4*9)+(3*0)+(2*9)+(1*0)=160
160 % 10 = 0
So 349090-90-0 is a valid CAS Registry Number.

349090-90-0Upstream product

349090-90-0Downstream Products

910486-27-0 N-(4-cyano-2-methylphenyl)methanesulfonamide

349090-90-0Relevant articles and documents

Synthesis and structural optimization of multiple H-bonding region of diarylalkyl (thio)amides as novel TRPV1 antagonists

Li, Fu-Nan,Kim, Nam-Jung,Chang, Dong-Jo,Jang, Jaebong,Jang, Hannah,Jung, Jong-Wha,Min, Kyung-Hoon,Jeong, Yeon-Su,Kim, Sun-Young,Park, Young-Ho,Kim, Hee-Doo,Park, Hyeung-Geun,Suh, Young-Ger

experimental part, p. 8149 - 8160 (2010/03/25)

Structural optimization of multiple H-bonding region and structure-activity relationship of diarylalkyl amides/thioamides as novel TRPV1 antagonists are described. In particular, we identified amide 34o and thioamides 35o and 35r, of which antagonistic activities were highly enhanced by an incorporation of cyano or vinyl-substituent to the multiple H-bonding region. They exhibited potent 45Ca2+ uptake inhibitions in rat DRG neuron with IC50s of 25, 32 and 28 nM, respectively.

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349090-90-0