349107-92-2

Basic information

• Product Name: Benzamide, N-(1,1-dimethylethyl)-3,4-dimethoxy-
• CAS NO: 349107-92-2
• Molecular Formula: C13H19NO3
• Molecular Weight: 237.299
• Mol File: 349107-92-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzamide, N-(1,1-dimethylethyl)-3,4-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(1,1-dimethylethyl)-3,4-dimethoxy-(349107-92-2)
• EPA Substance Registry System: Benzamide, N-(1,1-dimethylethyl)-3,4-dimethoxy-(349107-92-2)

Safety Data

• Hazardous Substances Data: 349107-92-2(Hazardous Substances Data)

Upstream product

• 2150-38-1 methyl 3,4-dimethoxybenzoate 
• 24824-54-2 3,4-dimethoxybenzoic anhydride 
• 75-64-9 tert-butylamine 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 93-07-2 Veratric acid 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 

Downstream Products

• 548-31-2 oxynitidine 
• 4038-14-6 3,4-dimethoxybenzophenone 
• 76291-01-5 N-tert-Butyl-5,6-dimethoxy-phthalamic acid methyl ester 
• 76290-99-8 N-tert-Butyl-4,5-dimethoxy-phthalamic acid methyl ester 

Relevant articles and documents

Radical mediated-direct conversion of aldehydes into acid bromides

A method of preparing acid bromides directly from aldehydes with Br3CCO2Et under radical conditions was developed. Aromatic aldehydes with electron-donating group were found to be more reactive than aromatic aldehydes with electron-w

Cobalt(III)-Catalyzed Construction of Benzofurans, Benzofuranones and One-Pot Orthogonal C?H Functionalizations to Access Polysubstituted Benzofurans

Benzofuran and benzofuranone derivatives have been synthesized through exclusive 5-exo-dig intramolecular hydroarylation using the amide-directed, cost-effective, high-valent Cp*CoIII-catalytic system. Challenging one-pot, orthogonal C?H functionalizations using two different electrophiles are also reported to afford polysubstituted benzofurans. Several valuable functional group interconversions along with removal of the amide directing group provide a route to access several diversely functionalized benzofurans. The mechanistic study suggests a reversible cobaltation step is operative here. (Figure presented.).

Cp?CoIII-Catalyzed syn-Selective C-H Hydroarylation of Alkynes Using Benzamides: An Approach Toward Highly Conjugated Organic Frameworks

Hydroarylation of internal alkynes by cost-effective CoIII-catalysis, directed by N-tert-butyl amides, is achieved to avail mono- or dihydroarylated amide products selectively in an atom and step economic way. Several important functional groups were tolerated under the reaction conditions, and syn-hydroarylation products were exclusively isolated. Notably, a 4-fold C-H hydroarylation provided a highly conjugated organic framework in one step. Kinetic study with extensive deuterium labeling experiments were performed to support the proposed mechanism.