3494-45-9

Basic information

• Product Name: 1-methoxy-4-methyl-benzene
• CAS NO: 3494-45-9
• Molecular Formula: C₈H₁₀O
• Molecular Weight: 121.159
• Mol File: 3494-45-9.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 265.9°Cat760mmHg
• Flash Point: 114.6°C
• Density: 1.23g/cm³
• CAS DataBase Reference: 1-methoxy-4-methyl-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methoxy-4-methyl-benzene(3494-45-9)
• EPA Substance Registry System: 1-methoxy-4-methyl-benzene(3494-45-9)

Safety Data

• Hazardous Substances Data: 3494-45-9(Hazardous Substances Data)

Upstream product

• 109-99-9 tetrahydrofuran 
• 17988-20-4 methoxybenzyltrimethylsilane radical cation 
• 67-56-1 methanol 
• 17988-20-4 C₁₁H₁₈OSi⁽¹⁺⁾ 
• 123621-29-4 C₁₄H₂₄OSi⁽¹⁺⁾ 
• 104-01-8 4-Methoxyphenylacetic acid 
• 104-93-8 p-methylanizole 
• 156-38-7 4-hydroxyphenylacetate 
• 105-13-5 4-Methoxybenzyl alcohol 
• 119-61-9 benzophenone 
• 27396-21-0 (p-Methoxyphenyl)-peressigsaeure-tert.-butylester 
• 3229-40-1 phthalimide N-oxyl 
• 2746-25-0 p-Methoxybenzyl bromide 
• 4985-62-0 phenylthiyl 

Downstream Products

• 1657-55-2 1,2-bis(4-methoxyphenyl)ethane 

Relevant articles and documents

Photodissociation of C-H and C-O bonds of p-methoxytoluene and p-methoxybenzyl alcohol in solution

The photodissociation of p-methoxytoluene and p-methoxybenzyl alcohol at 266 nm in n-heptane solution is studied by nanosecond fluorescence and absorption spectroscopy. The formation of a p-methoxybenzyl radical is identified by its fluorescence which is

Kinetic Study of the Phthalimide N-Oxyl Radical in Acetic Acid. Hydrogen Abstraction from Substituted Toluenes, Benzaldehydes, and Benzyl Alcohols

The phthalimide N-oxyl (PINO) radical was generated by the oxidation of N-hydroxyphthalimide (NHPI) with Pb(OAc)4 in acetic acid. The molar absorptivity of PINO. is 1.36 × 103 L mol -1 cm-1 at λmax 382 nm. The PINO radical decomposes slowly with a second-order rate constant of 0.6 ± 0.1 L mol-1 s-1 at 25°C. The reactions of PINO . with substituted toluenes, benzaldehydes, and benzyl alcohols were investigated under an argon atmosphere. The second-order rate constants were correlated by means of a Hammett analysis. The reactions with toluenes and benzyl alcohols have better correlations with σ+ (ρ = -1.3 and -0.41), and the reaction with benzaldehydes correlates better with σ (ρ = -0.91). The kinetic isotope effect was also studied and significantly large values of kH/kD were obtained: 25.0 (p-xylene), 27. 1 (toluene), 27.5 (benzaldehyde), and 16.9 (benzyl alcohol) at 25°C. From the Arrhenius plot for the reactions with p-xylene and p-xylene-d10, the difference of the activation energies, EaD - E aH, was 12.6 ± 0.8 kJ mol-1 and the ratio of preexponential factors, AH/AD, was 0.17 ± 0.05. These findings indicate that quantum mechanical tunneling plays an important role in these reactions.

Secondary α-Deuterium Kinetic Isotope Effects Signifying a Polar Transition State in the Thermolysis of Ring-Substituted tert-Butyl Phenylperacetates

Several ring-substituted tert-butyl phenylperacetates (YC6H4CH2CO3But) and their deuterated versions (YC6H4CD2CO3But) were prepared (Y: p-OCH3, p-CH3, p-H, and p-NO2). Thermolyses at 80°C in CDCl3 showed excellent first-order kinetics. The rates have been measured as kYH × 104 and kYD × 104 s-1: 11.9 and 9.20 (p-OCH3), 2.64 and 2.22 (p-CH3), 1.06 and 0.93 (p-H), 0.164 and 0.156 (p-NO2). Hammett correlations were derived to yield ρYH+ = -1.17 and ρYD+ = -1.12. However, better Hammett plots were obtained with three points (p-OCH3, p-CH3, and p-H) showing ρYH+ = -1.35 and ρYD+ = -1.28. SDKIE was calculated as 1.293 (p-OCH3), 1.189 (p-CH3), 1.140 (p-H), and 1.051 (p-NO2), showing substantial substituent effects. Values of kYH/kYD for p-NO2 showed little temperature dependence. Hammett correlations and SDKIE were derived from the same kinetic entity that is the bond cleavage.