349411-89-8Relevant articles and documents
Synthesis and biological evaluation of benzamides and benzamidines: Structural requirement of a pyrimidine ring for inhibition of EGFR tyrosine kinase
Asano, Toru,Yoshikawa, Tomohiro,Nakamura, Hiroyuki,Uehara, Yoshimasa,Yamamoto, Yoshinori
, p. 2299 - 2302 (2007/10/03)
The benzamides 1 and the benzamidines 2-3 were synthesized as the mimics of 4-anilinoquinazolines, which possess inhibition of epidermal growth factor receptor (EGFR) tyrosine kinase, and tested for cytotoxicity toward A431 and inhibitory activity toward