349456-93-5

Basic information

• Product Name: 4-[(3-methoxy-benzylidene) amino]-benzoic acid methyl ester
• Synonyms: 4-[(3-methoxy-benzylidene) amino]-benzoic acid methyl ester
• CAS NO: 349456-93-5
• Molecular Weight: 269.3
• Mol File: 349456-93-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-[(3-methoxy-benzylidene) amino]-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(3-methoxy-benzylidene) amino]-benzoic acid methyl ester(349456-93-5)
• EPA Substance Registry System: 4-[(3-methoxy-benzylidene) amino]-benzoic acid methyl ester(349456-93-5)

Safety Data

• Hazardous Substances Data: 349456-93-5(Hazardous Substances Data)

Upstream product

• 591-31-1 3-methoxy-benzaldehyde 
• 94-09-7 p-aminoethylbenzoate 
• 619-45-4 4-methoxycarbonyl aniline 

Downstream Products

• 1094338-77-8 C₁₆H₁₇NO₃ 
• 1343458-62-7 (3-hydroxy-3-methyl-pyrrolidin-1-yl)-[2-(3-methoxy-phenyl)-3,3-dimethyl-1,2,3,4-tetrahydro-quinolin-6-yl]-methanone 
• 1343458-73-0 2-(3-methoxy-phenyl)-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid 
• 1343458-71-8 2-(3-methoxy-phenyl)-3,3-dimethyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid methyl ester 

Relevant articles and documents

NOVEL 3,3-DIMETHYL TETRAHYDROQUINOLINE DERIVATIVES

A compound of formula (I) as well as pharmaceutically acceptable salt thereof, wherein R1 to R5 have the significance given in claim 1, can be used as a medicament.

Design, synthesis, and biological evaluation of benzylamino-methanone based cholesteryl ester transfer protein inhibitors

Cholesteryl ester transfer protein (CETP) is a glycoprotein involved in transporting lipoprotein particles and neutral lipids between high-density lipoprotein (HDL) and low density lipoproteins (LDL) and therefore its a proper target for treating dyslipidemia and related disorders. Guided by our previosuly-reported pharmacophore and QSAR models for CETP inhibition, we synthesized and bioassayed a series of benzylamino-methanones. The most potent illustrated 30% CETP inhibition at 10 μM.