34987-31-0

Basic information

• Product Name: 2-CYCLOHEXYL-1,4-NAPHTHOQUINONE
• Synonyms: 2-CYCLOHEXYL-1,4-NAPHTHOQUINONE
• CAS NO: 34987-31-0
• Molecular Formula: C₁₆H₁₆O₂
• Molecular Weight: 240.3
• Mol File: 34987-31-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 390.6 °C at 760 mmHg
• Flash Point: 146.4 °C
• Appearance: /
• Density: 1.197 g/cm³
• Vapor Pressure: 2.62E-06mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 2-CYCLOHEXYL-1,4-NAPHTHOQUINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYCLOHEXYL-1,4-NAPHTHOQUINONE(34987-31-0)
• EPA Substance Registry System: 2-CYCLOHEXYL-1,4-NAPHTHOQUINONE(34987-31-0)

Safety Data

• Hazardous Substances Data: 34987-31-0(Hazardous Substances Data)

Usage

General Description

2-CYCLOHEXYL-1,4-NAPHTHOQUINONE is a chemical compound with the molecular formula C18H18O2. It is a naphthoquinone derivative and is commonly used as a reactant in organic synthesis and as a precursor to various derivatives. It is also used in the production of dyes, antioxidants, and pharmaceuticals. This chemical is known to have potential applications in the field of medicine due to its antimicrobial and anti-inflammatory properties, and it is currently being studied for its potential therapeutic effects. However, it is important to handle this chemical with care as it can be hazardous if not properly handled and stored.

InChI:InChI=1/C16H16O2/c17-15-10-14(11-6-2-1-3-7-11)16(18)13-9-5-4-8-12(13)15/h4-5,8-11H,1-3,6-7H2

Upstream product

• 859986-44-0 2-cyclohexyl-5,8-dihydro-naphthalene-1,4-diol 
• 34987-30-9 2-(cyclohexyl)-1,4-di-(hydroxy)-naphthalene 
• 35448-12-5 2-(cyclohexyloxy)-2-oxoacetic acid 
• 130-15-4 [1,4]naphthoquinone 
• 98-89-5 Cyclohexanecarboxylic acid 
• 931-48-6 2-cyclohexylacetylene 
• 108-86-1 bromobenzene 
• 591-51-5 phenyllithium 
• 106-99-0 buta-1,3-diene 
• 4900-63-4 1-methoxy-4-nitronaphthalene 
• 60754-49-6 1,1-dibromo-2-cyclohexylethene 
• 2043-61-0 cyclohexanecarbaldehyde 
• 1088-01-3 tricyclohexylborane 
• 4441-56-9 cyclohexylboronic acid 

Downstream Products

• 41245-70-9 1a-cyclohexyl-1a,7a-dihydronaphth<2,3b>oxirene-2,7-dione 
• 73377-78-3 (+)-2-Cyclohexyl-1,4-naphthoquinone 2,3-epoxide 
• 105016-64-6 (2S,3R)-2-cyclohexyl-2,3-epoxy-1,4-naphthoquinone 
• 73377-78-3 (2R,3S)-2-cyclohexyl-2,3-epoxy-1,4-naphthoquinone 
• 41245-70-9 7a-Cyclohexyl-1a,7a-dihydro-1-oxa-cyclopropa[b]naphthalene-2,7-dione 
• 4042-30-2 parvaquone 
• 54812-04-3 2‐cyclohexyl‐3‐methylnaphthalene‐1,4‐dione 

Relevant articles and documents

Simple and effective route for synthesis of parvaquone, an antiprotozoal drug

Parvaquone, an antiprotozoal agent against Theileria parva, was synthesized in 33.8% overall yield by using cheap, commercially available raw materials. A key intermediate, 2-cyclohexyl-1-naphthol, was synthesized in 86% yield by cyclohexylation of 1-naphthol and further converted into parvaquone in good yield through reaction sequences such as oxidation and epoxidation followed by isomerization.

Quinone C-H Alkylations via Oxidative Radical Processes

A brief survey of radical additions to quinones is reported. Carboxylic acids, aldehydes, and unprotected amino acids are compared as alkyl radical precursors for the mono- or bis- C-H alkylation of several quinones. Two methods for radical initiation are discussed comparing inorganic persulfates and Selectfluor as stoichiometric oxidants. Kinetic analysis reveals dramatic differences in the rate of radical initiation depending on the identity of the radical precursor and oxidant. Synthetic strategies for efficiently producing alkyl-quinones are discussed in the context of selecting optimum radical precursors and initiators depending on quinone identity and functional groups present.

Naphthoquinone Derivatives, Benzoquinone Derivatives, and Anthracenedione Derivatives, Their Use and Novel Method for Preparation

The present invention relates to: a novel manufacturing method of quinone derivatives or anthracenedione derivatives by a copper-catalyzed cross-dehydrogenation coupling reaction of naphthoquinone, benzoquinone or anthracenedione compounds with various cycloalkanes; naphthoquinone derivatives, benzoquinone derivatives and anthracenedione derivatives; and uses thereof. According to the novel manufacturing method of the present invention, since the naphthoquinone derivatives, benzoquinone derivatives or anthracenedione derivatives can be prepared in one step, manufacturing efficiency is improved and cost and time can be saved, and the derivatives according to the present invention can be variously used as an animal medicine.COPYRIGHT KIPO 2019