350241-80-4

Basic information

• Product Name: FMOC-TYR(2-CLTRT)-OH
• Synonyms: FMOC-L-TYR(CLT)-OH;FMOC-O-2-CHLOROTRITYL-L-TYROSINE;FMOC-TYR(2-CLTRT)-OH;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-2-CHLOROTRITYL-L-TYROSINE;N-ALPHA-FMOC-O-2-CHLOROTRITYL-L-TYROSINE;Fmoc-L-Tyr(2-ClTrt)-OH;Fmoc-O-2-chlorotrityl-L-tyrosine≥ 99% (HPLC)
• CAS NO: 350241-80-4
• Molecular Formula: C43H34ClNO5
• Molecular Weight: 680.19
• Mol File: 350241-80-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 846.9±65.0 °C(Predicted)
• Appearance: /
• Density: 1.290±0.06 g/cm3(Predicted)
• Storage Temp.: 0-6°C
• PKA: 2.94±0.10(Predicted)
• CAS DataBase Reference: FMOC-TYR(2-CLTRT)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-TYR(2-CLTRT)-OH(350241-80-4)
• EPA Substance Registry System: FMOC-TYR(2-CLTRT)-OH(350241-80-4)

Safety Data

• Hazardous Substances Data: 350241-80-4(Hazardous Substances Data)

Usage

Description

FMOC-TYR(2-CLTRT)-OH is a chemical compound used in the field of peptide synthesis. It is a protected amino acid derivative, where the side-chain ClTrt group can be removed with 1% TFA/5% TIS in DCM. This allows the side-chain hydroxyl group to be selectively modified while the derivative is attached to the solid support. FMOC-TYR(2-CLTRT)-OH is a white to yellow powder in appearance.

Uses

1. Used in Peptide Synthesis:
FMOC-TYR(2-CLTRT)-OH is used as a protected amino acid building block for the synthesis of peptides. The ClTrt group provides protection to the side-chain hydroxyl group, allowing for selective modification during the peptide synthesis process.
2. Used in Pharmaceutical Research:
FMOC-TYR(2-CLTRT)-OH is used as a research tool in the development of new pharmaceuticals. Its ability to be selectively modified while attached to a solid support makes it a valuable compound for exploring the structure-activity relationships of potential drug candidates.
3. Used in Chemical Synthesis:
FMOC-TYR(2-CLTRT)-OH can be used as a starting material or intermediate in the synthesis of various chemical compounds, particularly those involving the modification of the side-chain hydroxyl group.
4. Used in Analytical Chemistry:
FMOC-TYR(2-CLTRT)-OH can be employed as a reference compound or standard in analytical chemistry, particularly in the analysis of amino acid derivatives and related compounds.
5. Used in Material Science:
FMOC-TYR(2-CLTRT)-OH may also find applications in material science, where its unique chemical properties could be utilized in the development of new materials with specific functionalities.