35088-89-2

Basic information

• Product Name: 1-(4-Methoxyphenylsulfonyl)piperidine, 97%
• Synonyms: 1-(4-Methoxyphenylsulfonyl)piperidine, 97%
• CAS NO: 35088-89-2
• Molecular Formula: C₁₂H₁₇NO₃S
• Molecular Weight: 255.33328
• Mol File: 35088-89-2.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 392.2°Cat760mmHg
• Flash Point: 191°C
• Appearance: /
• Density: 1.222g/cm³
• Vapor Pressure: 2.34E-06mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: 1-(4-Methoxyphenylsulfonyl)piperidine, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Methoxyphenylsulfonyl)piperidine, 97%(35088-89-2)
• EPA Substance Registry System: 1-(4-Methoxyphenylsulfonyl)piperidine, 97%(35088-89-2)

Safety Data

• Hazardous Substances Data: 35088-89-2(Hazardous Substances Data)

Usage

Description

1-(4-Methoxyphenylsulfonyl)piperidine, 97% is a sulfonyl piperidine derivative with a methoxyphenyl group attached to the sulfur atom. It is a chemical compound with a purity of 97%, making it suitable for precise and reliable synthetic applications in both academic and industrial settings. This versatile compound is commonly used as a building block in organic synthesis and pharmaceutical research due to its potential pharmacological properties and reactivity.

Uses

Used in Pharmaceutical Research:
1-(4-Methoxyphenylsulfonyl)piperidine, 97% is used as a building block for the development of various therapeutic agents. Its versatile reactivity and potential pharmacological properties make it a valuable component in the creation of drugs for the treatment of neurological disorders, pain management, and other medical conditions.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(4-Methoxyphenylsulfonyl)piperidine, 97% serves as a key intermediate compound. Its unique structure allows for further chemical reactions and modifications, enabling the synthesis of a wide range of complex organic molecules for various applications.

InChI:InChI=1/C12H17NO3S/c1-16-11-5-7-12(8-6-11)17(14,15)13-9-3-2-4-10-13/h5-8H,2-4,9-10H2,1H3

Upstream product

• 110-89-4 piperidine 
• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 
• 35856-62-3 1-piperidinesulfonyl chloride 
• 100-66-3 methoxybenzene 
• 154853-46-0 2,4-dinitrophenyl 4-methoxybenzenesulfonate 
• 663175-94-8 pentafluorophenyl 4-methoxyphenylsulfonate ester 
• 261789-26-8 4-nitrophenyl 4-methoxybenzenesulfonate 
• 696-62-8 para-iodoanisole 
• 6462-50-6 sodium 4-methoxybenzenesulfinate 
• 5720-07-0 4-methoxyphenylboronic acid 
• 766-09-6 1-ethyl-piperidine 
• 1950-68-1 4-methoxybenzenesulfonyl hydrazide 

Downstream Products

• 99986-71-7 4-(piperidin-1-ylsulfonyl)phenol 

Relevant articles and documents

Iodine-catalyzed sulfonylation of sulfonyl hydrazides with: Tert -amines: A green and efficient protocol for the synthesis of sulfonamides

This study provides a direct, sustainable and eco-friendly method for the synthesis of various sulfonamides via the sulfonylation of sulfonyl hydrazides with tert-amines. The method utilizes sulfonyl hydrazides to oxidize and couple with tertiary amines through selective cleavage of C-N bonds. In this reaction, molecular iodine was used as the catalyst and t-butyl hydroperoxide was used as the oxidant.

TBAI-catalyzed selective synthesis of sulfonamides and β-aryl sulfonyl enamines: coupling of arenesulfonyl chlorides and sodium sulfinates with tert-amines

A simple, practical and metal-free method has been developed for the synthesis of sulfonamides and β-arylsulfonyl enamines via the selective cleavage of C-N and C-H bonds through the iodine-catalyzed oxidation of arenesulfonyl chlorides and sodium sulfinates with tert-amines. The method uses commercially available inexpensive catalysts and oxidants, and has a wide substrate scope and operational simplicity.

Method for synthesizing benzenesulfonamide compound by using benzenesulfonyl chloride compound and secondary amine through metal-free catalysis

The invention provides a method for synthesizing a benzenesulfonamide compound by using a benzenesulfonyl chloride compound and secondary amine through metal-free catalysis. The method comprises the following steps: taking the benzenesulfonamide compound