35090-95-0

Basic information

• Product Name: PIPERIDIN-4-YL-PYRROLIDIN-1-YL-METHANONE
• Synonyms: 4-(1-Pyrrolidinylcarbonyl)piperidine;PIPERIDIN-4-YL-PYRROLIDIN-1-YL-METHANONE;4-PIPERIDINYL(1-PYRROLIDINYL)METHANONE;4-(PYRROLIDIN-1-YLCARBONYL)PIPERIDINE;AKOS B025051;CHEMBRDG-BB 4003425;ART-CHEM-BB B025051;4-(PYRROLIDIN-1-YLCARBONYL)PIPERIDINE HYDROCHLORIDE
• CAS NO: 35090-95-0
• Molecular Formula: C₁₀H₁₈N₂O
• Molecular Weight: 182.26
• Mol File: 35090-95-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 45 °C
• Boiling Point: 335.272 °C at 760 mmHg
• Flash Point: 156.567 °C
• Appearance: /
• Density: 1.075 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.513
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: PIPERIDIN-4-YL-PYRROLIDIN-1-YL-METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: PIPERIDIN-4-YL-PYRROLIDIN-1-YL-METHANONE(35090-95-0)
• EPA Substance Registry System: PIPERIDIN-4-YL-PYRROLIDIN-1-YL-METHANONE(35090-95-0)

Safety Data

• Hazard Codes: C,Xi
• Statements: 20/21/22-41-37/38
• Safety Statements: 22-36/37/39-39-26
• HazardClass: IRRITANT
• Hazardous Substances Data: 35090-95-0(Hazardous Substances Data)

Usage

General Description

PIPERIDIN-4-YL-PYRROLIDIN-1-YL-METHANONE is a chemical compound containing a piperidine and pyrrolidine ring structure, as well as a ketone functional group. It is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. The compound has potential applications in the production of drugs, especially those targeting the central nervous system. Additionally, it is utilized in research and development for the creation of new chemical entities and drug candidates. However, it is important to handle PIPERIDIN-4-YL-PYRROLIDIN-1-YL-METHANONE with caution, as it may pose certain hazards if not properly handled and managed.

InChI:InChI=1/C10H18N2O/c13-10(12-7-1-2-8-12)9-3-5-11-6-4-9/h9,11H,1-8H2

Upstream product

• 86542-83-8 (pyridin-4-yl)(pyrrolidin-1-yl)methanone 
• 147635-68-5 4-(Pyrrolidine-1-carbonyl)-piperidine-1-carboxylic acid benzyl ester 
• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 188979-06-8 tert-butyl 4-(pyrrolidine-1-carbonyl)piperidine-1-carboxylate 

Downstream Products

• 86543-10-4 4-(Pyrrolidine-1-carbonyl)-piperidine-1-carbothioic acid (2-cyano-4,5-dimethoxy-phenyl)-amide 
• 80030-52-0 N-(2-Cyano-4,5-dimethoxy-phenyl)-4-(pyrrolidine-1-carbonyl)-piperidine-1-carboximidothioic acid methyl ester 
• 1255716-09-6 N-(4-chloro-benzyl)-N-{3-[4-(pyrrolidine-1-carbonyl)-piperidine-1-carbonyl]-phenyl}-benzenesulfonamide 
• 1258281-61-6 2-{2-chloro-5-[4-(pyrrolidine-1-carbonyl)-piperidin-1-yl]-phenyl}-5-methoxy-benzoimidazole-1-carboxylic acid tert-butyl ester 
• 683772-11-4 4-(pyrrolidin-1-ylmethyl)piperidine 

Relevant articles and documents

Design, synthesis and antitubercular evaluation of benzothiazinones containing a piperidine moiety

We herein report the design and synthesis of benzothiazinones containing a piperidine moiety as new antitubercular agents based on the structure feature of IMB-ZR-1 discovered in our lab. Some of them were found to have good in vitro activity (MIC 1 μg/

AZAARENE DERIVATIVES

A compound represented by the general formula: wherein X1 represents a nitrogen atom or a group represented by the formula -CR10=; X2 represents a nitrogen atom or a group represented by the formula -CR11=; Y represents an oxygen atom or the like; R1 represents a C1-6 alkoxy group, an optionally substituted C6-10 aryloxy group, a group represented by the formula -NR12aR12b or the like; R2 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like; R3, R4, R5, R6, R7, R8, R10 and R11 each independently represent a hydrogen atom, a halogen atom, an optionally substituted C1-6 alkyl group, or the like; R9 represents a group represented by the formula -NR16aR16b or the like; and R12a, R12b, R16a and R16b each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, a salt thereof, or a hydrate of the foregoing.