35113-87-2

Basic information

• Product Name: N-ethyl-N,4-dimethylaniline
• CAS NO: 35113-87-2
• Molecular Formula: C₁₀H₁₅N
• Molecular Weight: 149.2328
• Mol File: 35113-87-2.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 231.1°C at 760 mmHg
• Flash Point: 92.9°C
• Density: 0.931g/cm³
• Vapor Pressure: 0.0633mmHg at 25°C
• Refractive Index: 1.536
• CAS DataBase Reference: N-ethyl-N,4-dimethylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-ethyl-N,4-dimethylaniline(35113-87-2)
• EPA Substance Registry System: N-ethyl-N,4-dimethylaniline(35113-87-2)

Safety Data

• Hazardous Substances Data: 35113-87-2(Hazardous Substances Data)

Upstream product

• 622-57-1 N-ethyl-p-tolylamine 
• 74-88-4 methyl iodide 
• 612-03-3 4-(N-methylacetamido)toluene 
• 616-38-6 carbonic acid dimethyl ester 
• 74-96-4 ethyl bromide 
• 623-08-5 N-methyl-p-toluidine 

Downstream Products

• 612-03-3 4-(N-methylacetamido)toluene 
• 15296-56-7 N-ethyl-N-(4-methylphenyl)formamide 
• 6932-93-0 N-ethyl-N-(p-tolyl)acetamide 
• 116016-00-3 (4-{Ethoxycarbonyl-[(ethyl-p-tolyl-amino)-methyl]-amino}-phenyl)-carbamic acid ethyl ester 
• 5466-93-3 diethyl 1,4-phenylenediamine-N,N'-dicarboxylate 
• 1105066-14-5 5-{[ethyl(4-methylphenyl)amino]methyl}-2(5H)-furanone 
• 622-57-1 N-ethyl-p-tolylamine 
• 939-28-6 N-ethyl-N-(p-tolyl)nitrous amide 
• 937-24-6 N-methyl-N-nitroso-p-toluidine 

Relevant articles and documents

Aminomethylation of Aryl Bromides by Nickel-Catalyzed Electrochemical Redox Neutral Cross Coupling

We develop an electrochemical nickel-catalyzed aminomethylation of aryl bromides under mild conditions. The convergent paired electrolysis makes full use of anode and cathode processes, free of a terminal oxidant, a sacrificial anode, a metal reductant, and a prefunctionalized radical precursor. In addition, this method exhibits wide functional group tolerance (63 examples), including some sensitive substituents and aromatic heterocycles. This redox neutral cross coupling provides a more environmentally friendly and synthetic practical protocol for forging C(sp2)–C(sp3) bonds.

Sodium Triethylborohydride-Catalyzed Controlled Reduction of Unactivated Amides to Secondary or Tertiary Amines

The first transition-metal-free catalytic protocol for controlled reduction of amide functions using cheap and bench-stable hydrosilanes as reducing agents has been established. By altering the hydrosilane and solvent, the new method enables the selective cleavage of unactivated C-O bonds in amides and allows the C-N bonds to selectively break via the deacylated cleavage. Overall, this novel process may offer a versatile alternative to current methodologies employing stoichiometric metal systems for the controlled reduction of carboxamides.

B(C6F5)3-Catalyzed Deoxygenative Reduction of Amides to Amines with Ammonia Borane

The first B(C6F5)3-catalyzed deoxygenative reduction of amides into the corresponding amines with readily accessible and stable ammonia borane (AB) as a reducing agent under mild reaction conditions is reported. This metal-free protocol provides facile access to a wide range of structurally diverse amine products in good to excellent yields, and various functional groups including those that are reduction-sensitive were well tolerated. This new method is also applicable to chiral amide substrates without erosion of the enantiomeric purity. The role of BF3 ? OEt2 co-catalyst in this reaction is to activate the amide carbonyl group via the in situ formation of an amide-boron adduct. (Figure presented.).