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35118-50-4

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35118-50-4 Usage

Description

MONOISOPROPYLPHTHALATE, also known as a phthalic acid monoester, is a chemical compound derived from the formal condensation of one of the carboxy groups of phthalic acid with the hydroxy group of isopropanol. It possesses anti-estrogenic activities at concentrations higher than 10^-4 M and is utilized in the synthesis of various compounds, such as SB-462795, a cathepsin K inhibitor.

Uses

Used in Pharmaceutical Industry:
MONOISOPROPYLPHTHALATE is used as a chemical intermediate for the preparation of SB-462795, a cathepsin K inhibitor, which has potential applications in the treatment of conditions related to bone resorption, such as osteoporosis.
Used in Research Applications:
In the field of research, MONOISOPROPYLPHTHALATE is used as an anti-estrogenic agent at concentrations higher than 10^-4 M. This property makes it a valuable tool for studying the effects of estrogen on various biological processes and for developing new drugs targeting estrogen-related pathways.
Used in Chemical Synthesis:
MONOPROPYLPHTHALATE is employed as a key component in the synthesis of various chemical compounds, contributing to the development of new materials and products in the chemical industry.

Check Digit Verification of cas no

The CAS Registry Mumber 35118-50-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,1,1 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 35118-50:
(7*3)+(6*5)+(5*1)+(4*1)+(3*8)+(2*5)+(1*0)=94
94 % 10 = 4
So 35118-50-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H12O4/c1-7(2)15-11(14)9-6-4-3-5-8(9)10(12)13/h3-7H,1-2H3,(H,12,13)

35118-50-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-propan-2-yloxycarbonylbenzoic acid

1.2 Other means of identification

Product number -
Other names Phthalsaeure-monoisopropylester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35118-50-4 SDS

35118-50-4Relevant articles and documents

Diorganotin complexes of carboxylates: Synthesis and characterization

Chilwal, Asha,Deep, Gagan,Malhotra, Priti,Narula

, p. 1046 - 1057 (2013)

Diorganotin complexes of monoisopropyl and monomethyl nadiate, succinate, and phthalate were synthesized and characterized by elemental analysis, FT-IR, 1H NMR, 13C NMR, and 119Sn NMR spectroscopic techniques. The spectroscopic investigation demonstrated that carboxylate is bidentate in the diorganotin complexes. On the basis of 1J(119Sn-13C) and 2J(119Sn-1H) values, C-Sn-C bond angles were also calculated. The newly synthesized complexes were also screened for their antibacterial activities against Gram-positive and Gram-negative pathogenic strains of bacteria.

CYCLIC PHOSPHATE COMPOUNDS

-

Paragraph 0195-0197, (2020/11/04)

Provided herein are cyclic phosphate compounds, their preparation and their uses, such as treating liver diseases or conditions or a disease or condition in which the physiological or pathogenic pathways involve the liver.

Practical selective monohydrolysis of bulky symmetric diesters: Comparing with sonochemistry

Shi, Jianjun,Zhao, Tian,Niwayama, Satomi

, p. 6815 - 6820 (2018/10/20)

The conditions of the practical selective monohydrolysis of symmetric diesters we previously reported have been modified and applied to selective monohydrolysis of bulky symmetric diesters. While ultrasound is generally considered effective for two-phase reactions, its effect actually turned out to be rather marginal. Instead, use of a larger proportion of a polar aprotic co-solvent, DMSO, and aqueous KOH helped enhance the reaction rates and improve the yields of the half-esters. The reactions are simple, mild and practical without special devices.

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