3514-48-5

Basic information

• Product Name: (25R)-2α,3β-Dihydroxy-5α-spirost-9(11)-en-12-one
• Synonyms: (25R)-2α,3β-Dihydroxy-5α-spirost-9(11)-en-12-one;9-Dehydromanogenin
• CAS NO: 3514-48-5
• Molecular Formula: C₂₇H₄₀O₅
• Molecular Weight: 444.61
• Mol File: 3514-48-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (25R)-2α,3β-Dihydroxy-5α-spirost-9(11)-en-12-one(CAS DataBase Reference)
• NIST Chemistry Reference: (25R)-2α,3β-Dihydroxy-5α-spirost-9(11)-en-12-one(3514-48-5)
• EPA Substance Registry System: (25R)-2α,3β-Dihydroxy-5α-spirost-9(11)-en-12-one(3514-48-5)

Safety Data

• Hazardous Substances Data: 3514-48-5(Hazardous Substances Data)

Downstream Products

• 564-43-2 manogenin 

Relevant articles and documents

Cytotoxic steroidal glycosides from the underground parts of Hosta ventricosa

A phytochemical study on the underground parts of Hosta ventricosa yielded one new spirostanol saponin (1), two new furostanol saponins (2 and 3), and one new pregnane glycoside (4), along with three known compounds (5?7). Their structures were elucidated on the basis of chemical and spectroscopic analysis. All isolated compounds were evaluated for their cytotoxic effects against five human cancer cell lines (HL-60, A-549, SMMC-7721, MCF-7, and SW-480). Compounds 1, 2, and 5?7 showed cytotoxic activities with IC50 values of 3.21-17.06 μM.