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35142-05-3

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35142-05-3 Usage

Safety Profile

An experimental teratogen. Otherexperimental reproductive effects. Mutation data reported.When heated to decomposition it emits acrid smoke andfumes.

Check Digit Verification of cas no

The CAS Registry Mumber 35142-05-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,1,4 and 2 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 35142-05:
(7*3)+(6*5)+(5*1)+(4*4)+(3*2)+(2*0)+(1*5)=83
83 % 10 = 3
So 35142-05-3 is a valid CAS Registry Number.
InChI:InChI=1/C17H12O5/c1-20-13-4-2-3-10-9(13)5-6-11-12(17(18)19)7-14-16(15(10)11)22-8-21-14/h2-7H,8H2,1H3,(H,18,19)

35142-05-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-methoxynaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid

1.2 Other means of identification

Product number -
Other names Aristolsaeure I

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35142-05-3 SDS

35142-05-3Relevant articles and documents

Conversion of aristolochic acid i into aristolic acid by reaction with cysteine and glutathione: Biological implications

Priestap, Horacio A.,Barbieri, Manuel A.

, p. 965 - 968 (2013)

Aristolochic acid I (AA-I), naturally occurring in Aristolochia plants, is a potent nephrotoxin and carcinogen. Here we report that AA-I suffers hydrogenolysis with loss of the nitro group by reaction with cysteine or glutathione to give aristolic acid. Since the reaction can proceed in aqueous solutions at pH 7.0 and 37 C, it is inferred that it may also occur in biological systems and contribute to the nephrotoxic effects induced by AA-I.

Semisynthetic derivatives of aristolchocic acids I and II as reference compounds for metabolites in the rat

Krumbiegel,Roth

, p. 264 - 270 (2007/10/02)

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