3517-38-2

Basic information

• Product Name: 3beta,17-dihydroxypregn-5-en-20-one 3,17-di(acetate)
• Synonyms: 3beta,17-dihydroxypregn-5-en-20-one 3,17-di(acetate);3β,17-Bis(acetyloxy)pregn-5-en-20-one;3β,17-Diacetoxypregna-5-ene-20-one;3β,17-Dihydroxypregna-5-ene-20-one 3,17-diacetate
• CAS NO: 3517-38-2
• Molecular Formula: C₂₅H₃₆O₅
• Molecular Weight: 449.55708
• EINECS: 222-524-0
• Mol File: 3517-38-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 495.6°Cat760mmHg
• Flash Point: 211°C
• Appearance: /
• Density: 1.14g/cm³
• CAS DataBase Reference: 3beta,17-dihydroxypregn-5-en-20-one 3,17-di(acetate)(CAS DataBase Reference)
• NIST Chemistry Reference: 3beta,17-dihydroxypregn-5-en-20-one 3,17-di(acetate)(3517-38-2)
• EPA Substance Registry System: 3beta,17-dihydroxypregn-5-en-20-one 3,17-di(acetate)(3517-38-2)

Safety Data

• Hazardous Substances Data: 3517-38-2(Hazardous Substances Data)

Usage

General Description

3beta,17-dihydroxypregn-5-en-20-one 3,17-di(acetate) is a synthetic steroid hormone and derivative of progesterone. It is a white, crystalline powder that is soluble in ethanol, chloroform, and ether. This chemical compound is commonly used in the production of pharmaceutical drugs, specifically in the manufacturing of hormonal contraceptives and hormone replacement therapy medications. Its chemical structure consists of two acetate groups attached to the 3 and 17 positions of the steroid backbone, providing stability and enhancing its pharmacokinetic properties. 3beta,17-dihydroxypregn-5-en-20-one 3,17-di(acetate) is important in the field of endocrinology and has numerous medical applications due to its ability to mimic and regulate hormonal functions.

Upstream product

• 108-21-4 Isopropyl acetate 
• 1863-39-4 3β-acetoxy-17α-hydroxy-5-pregnen-20-one 
• 387-79-1 17-Hydroxypregnenolone 
• 108-24-7 acetic anhydride 
• 2381-45-5 pregn-5-ene-3β,17α-diol-20-one 17-acetate 

Downstream Products

• 2381-45-5 pregn-5-ene-3β,17α-diol-20-one 17-acetate 
• 13258-29-2 3β,17α-Diacetoxypregn-5-en-7,20-dion 
• 903-67-3 Δ⁵-pregnene-3β,17α,20α-triol 
• 2204-13-9 Δ⁵-pregnene-3β,17α,20S-triol 
• 604-03-5 12β,17α-dihydroxyprogesterone 
• 979-02-2 16-dehydropregnenolone acetate 

Relevant articles and documents

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Microwave induced selective enolization of steroidal ketones and efficient acetylation of sterols in semisolid state

Under microwave irradiation steroidal enones, more specifically, position three carbonyls were efficiently and selectively converted to the corresponding enol acetates in the presence of additional enolizable carbonyl functions at other positions, using acetic anhydride and a catalytic amount of toluene-p-sulfonic acid. Acetylation of hydroxyl groups of the sterols, including those at the hindered positions, was near quantitative. Strictly anhydrous conditions were not a pre-requisite for acetylation and the reaction system easily tolerated up to 10% (v/v) moisture.