35207-71-7Relevant articles and documents
Interplay of theory and experiment: Reversal of the torquoselectivity of the electrocyclic ring opening of 3-acetylcyclobutene by a Lewis acid
Niwayama, Satomi
, p. 640 - 646 (1996)
Theoretical predictions, accompanied by firm experimental verification, are presented on the "torquoselectivity" of the thermal ring opening of 3-acetylcyclobutene (1). 3-Acetylcyclobutene was synthesized from commercially available 1,1-cyclobutanedicarboxylic acid. Thermolysis of 3-acetylcyclobutene resulted in a mixture of E- and Z-dienes with a slight preference for the E-diene. This preference was reversed by the Lewis acid, ZnI2, as predicted from theoretical calculations.
Expedient synthesis of cis- and trans-3-aminocyclobutanecarboxylic acids
Radchenko, Dmytro S.,Tkachenko, Anton,Grygorenko, Oleksandr O.,Komarov, Igor V.
, p. 1644 - 1649 (2011/06/23)
An expedient approach to cis- and trans-3-aminocyclobutanecarboxylic acids was developed starting from 1,1-cyclobutanedicarboxylic acid. Stereochemistry of the title compounds was established by nuclear Overhauser effect spectroscopy experiments.
SYNTHESIS OF SQ-32,829, A NEW NUCLEOSIDE ANTIVIRAL AGENT
Jacobs, G. A.,Tino, J. A.,Zahler, R.
, p. 6955 - 6958 (2007/10/02)
The guanine-containing cyclobutane nucleoside analog SQ-32,829 (1) was synthesized in 8 steps from 1,1-cyclobutanedicarboxylic acid(3).