352290-71-2

Basic information

• Product Name: 3-(2-amino-3-methyl-butyl)-1-(2,6-difluoro-benzyl)-5-(2-fluoro-3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione
• Synonyms: 3-(2-amino-3-methyl-butyl)-1-(2,6-difluoro-benzyl)-5-(2-fluoro-3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione
• CAS NO: 352290-71-2
• Molecular Weight: 461.484
• Mol File: 352290-71-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-amino-3-methyl-butyl)-1-(2,6-difluoro-benzyl)-5-(2-fluoro-3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-amino-3-methyl-butyl)-1-(2,6-difluoro-benzyl)-5-(2-fluoro-3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione(352290-71-2)
• EPA Substance Registry System: 3-(2-amino-3-methyl-butyl)-1-(2,6-difluoro-benzyl)-5-(2-fluoro-3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione(352290-71-2)

Safety Data

• Hazardous Substances Data: 352290-71-2(Hazardous Substances Data)

Upstream product

• 732282-79-0 {1-[3-(2,6-difluoro-benzyl)-5-(2-fluoro-3-methoxy-phenyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-ylmethyl]-2-methyl-propyl}-carbamic acid tert-butyl ester 
• 79069-14-0 tert-butyl [(1R)-1-(hydroxymethyl)-2-methylpropyl]carbamate 
• 732282-70-1 {1-[5-bromo-3-(2,6-difluoro-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-ylmethyl]-2-methyl-propyl}-carbamic acid tert-butyl ester 
• 352303-66-3 5-bromo-1-(2,6-difluoro-benzyl)-6-methyl-1H-pyrimidine-2,4-dione 

Relevant articles and documents

3-(2-Aminoalkyl)-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl) -6-methyluracils as orally bioavailable antagonists of the human gonadotropin releasing hormone receptor

Uracils possessing N-3 side chains derived from various amino alcohols were designed and synthesized as potent human gonadotropin releasing hormone receptor antagonists. The compounds herein presented displayed superior metabolic stability than their pred