352329-70-5Relevant articles and documents
Guanine base stabilized on the magnetic nanoparticles as recyclable catalyst “on water” for the synthesis of spirooxindole derivatives
Azizi, Zohre,Bashkar, Mohammad,Niknam, Khodabakhsh,Rezaei, Arash,Saberi, Dariush
, (2021/06/15)
Guanine stabilized on the surface of silica-modified magnetic nanoparticles, by the propyl group as a linker, (Fe3O4@SiO2-n-(propyl)-guanine), was prepared, identified and used as a recyclable base in the synthesis of novel spirooxindole compounds and highly substituted dihydro-2-oxopyrroles in aqueous media. Fe3O4@SiO2-n-(propyl)-guanine was characterized via some spectroscopic and microscopic techniques such as Infrared spectroscopy (IR), X-ray diffraction spectroscopy (XRD), Energy dispersive X-ray spectroscopy (EDX), Vibrating sample magnetometry (VSM), Scanning electron microscopy (SEM), High resolution transmission electron microscopy (HR-TEM), Thermo-gravimetric analysis (TGA) and NMR-detected hydrogen/deuterium (H/D) exchange technique. The synthesized nanocomposite was employed as a new base catalyst for the synthesis of some novel spirooxindole compounds and highly substituted dihydro-2-oxopyrroles in aqueous media with good to excellent yields. This heterogeneous base catalyst could be recycled and reused up to ten times without appreciable loss of activity.
An efficient one-pot multi-component synthesis of spirooxindoles using Fe3O4/g-C3N4 nanocomposite as a green and reusable catalyst in aqueous media
Kamali, Fatemeh,Shirini, Farhad
, (2020/12/15)
In this study, an efficacious method is described for the synthesis of spirooxindole derivatives using Fe3O4/g-C3N4 as a green catalyst. This is a one-pot three-component condensation in water as a clean and environmentally favorable media. The present procedure proposes various remarkable privileges such as mild reaction conditions, simple work-up procedure and environment friendly. Moreover, the catalyst used is easily recovered by the external magnetic field and reused without significant deterioration in catalytic activity after at least six times.
Synthesis of functionalized chromene and spirochromenes using L-proline-melamine as highly efficient and recyclable homogeneous catalyst at room temperature
Nagaraju, Sakkani,Paplal, Banoth,Sathish, Kota,Giri, Santanab,Kashinath, Dhurke
supporting information, p. 4200 - 4204 (2017/10/06)
An efficient and recyclable homogeneous catalyst is developed using commercially cheap L-proline and melamine for the synthesis of chromenes and spirochromenes (spirooxindoles) via multicomponent reactions at room temperature. Systematic studies were conducted in order to achieve desired reactivity and recyclability of the catalyst using various α-amino acids and aromatic amines as donor-acceptor pairs. Among the screened combinations, L-proline and melamine (3:1 ratio; 3 mol% on total weight) was found to be best catalyst to give the desired products with excellent yields (up to 99%) in very short times (1–15 min) at room temperature in DMSO as solvent. The catalyst was recovered by adding EtOAc and reused up to 5 cycles without losing the catalytic activity.
