352513-83-8 Usage
General Description
Semapimod, also known as CNI-1493, is a synthetic small molecule that acts as a potent and selective inhibitor of the pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-alpha). It works by suppressing the production and release of TNF-alpha, which is involved in the inflammatory response and plays a key role in various autoimmune and inflammatory diseases. Semapimod has shown promising potential as a therapeutic agent for conditions such as rheumatoid arthritis, inflammatory bowel disease, and sepsis. Its ability to modulate the immune system and reduce inflammation makes it a promising candidate for the treatment of a range of inflammatory conditions. Ongoing research is focused on further exploring its safety and efficacy in clinical trials.
Check Digit Verification of cas no
The CAS Registry Mumber 352513-83-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,2,5,1 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 352513-83:
(8*3)+(7*5)+(6*2)+(5*5)+(4*1)+(3*3)+(2*8)+(1*3)=128
128 % 10 = 8
So 352513-83-8 is a valid CAS Registry Number.
InChI:InChI=1/C34H52N18O2/c1-19(45-49-31(35)36)23-13-24(20(2)46-50-32(37)38)16-27(15-23)43-29(53)11-9-7-5-6-8-10-12-30(54)44-28-17-25(21(3)47-51-33(39)40)14-26(18-28)22(4)48-52-34(41)42/h13-18H,5-12H2,1-4H3,(H,43,53)(H,44,54)(H4,35,36,49)(H4,37,38,50)(H4,39,40,51)(H4,41,42,52)/b45-19+,46-20+,47-21+,48-22+
352513-83-8Relevant articles and documents
Guanylhydrazone salts, compositions, processes of making and methods of using
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Page/Page column 20, (2008/06/13)
The invention relates to pharmaceutically acceptable salts of guanylhydrazone-containing compounds, for example, Semapimod. The invention also relates to pharmaceutically acceptable compositions comprising the salts and methods for their use.
