35280-40-1

Basic information

• Product Name: Phenol, 4-bromo-2,6-bis[(5-bromo-2-hydroxyphenyl)methyl]-
• CAS NO: 35280-40-1
• Molecular Formula: C20H15Br3O3
• Molecular Weight: 543.049
• Mol File: 35280-40-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phenol, 4-bromo-2,6-bis[(5-bromo-2-hydroxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-bromo-2,6-bis[(5-bromo-2-hydroxyphenyl)methyl]-(35280-40-1)
• EPA Substance Registry System: Phenol, 4-bromo-2,6-bis[(5-bromo-2-hydroxyphenyl)methyl]-(35280-40-1)

Safety Data

• Hazardous Substances Data: 35280-40-1(Hazardous Substances Data)

Upstream product

• 106-41-2 4-bromo-phenol 
• 6296-63-5 4-bromo-2,6-bis(hydroxymethyl)phenol 
• 50-00-0 formaldehyd 

Downstream Products

• 2677-32-9 2,6-Bis-(2-hydroxy-benzyl)-phenol 

Relevant articles and documents

Solvent-free synthesis of trisphenols as starting precursors for the synthesis of calix[4]arenes using sulfonated multi-walled carbon nanotubes

The condensation of phenol derivatives (12 substrates) with 2,6-bis(hydroxymethyl)phenols (BMP) (6 examples) is reported using sulfonated multi-walled carbon nanotubes (SO3H@MWCNTs) under solvent-free conditions as starting precursors for the synthesis of macrocyclic molecules of calix[4]arenes. The new protocol provides a series of trisphenol derivatives (21 examples) in high yields (up to 94%) and relatively short reaction times (15-120 min). Also, direct synthesis of calix[4]arenes from different trisphenols by use of the catalyst was reported (5 examples). Furthermore, the synthesized calix[4]arene was obtained using a one-pot method from simple and easily available starting materials such as p-cresol for the synthesis of 5,11,17,23-tetramethylcalix[4]arene-25,26,27,28-tetraol. Also, in this process SO3H@MWCNTs can be reused for seven runs with almost consistent efficiency and can be recovered by easy filtration.

Synthesis of polyfunctional aromatic ring systems (phloroglucide analogs) under microwave irradiation

An efficient and rapid synthesis of phloroglucide analogs under microwave irradiation is described. The solid-phase condensation reaction of the 4-halo-2,6-bis(hydroxymethyl)phenols 1a,b with other substituted phenols in the presence of ZnCl2 afforded the target molecules in much higher yields than by classical solution-phase synthesis and allowed us to prepare new phloroglucide analogs possessing sensitive functional groups difficult to access by established means.