353258-35-2

Basic information

• Product Name: 8-CHLORO-6-(TRIFLUOROMETHYL)IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID
• Synonyms: 8-CHLORO-6-(TRIFLUOROMETHYL)IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID;2-Carboxy-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine
• CAS NO: 353258-35-2
• Molecular Formula: C₉H₄ClF₃N₂O₂
• Molecular Weight: 264.59
• Mol File: 353258-35-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Density: 1.71±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -5.17±0.41(Predicted)
• CAS DataBase Reference: 8-CHLORO-6-(TRIFLUOROMETHYL)IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 8-CHLORO-6-(TRIFLUOROMETHYL)IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID(353258-35-2)
• EPA Substance Registry System: 8-CHLORO-6-(TRIFLUOROMETHYL)IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID(353258-35-2)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 353258-35-2(Hazardous Substances Data)

Usage

General Description

8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid is a chemical compound that belongs to the class of pyridine carboxylic acids and is characterized by the presence of a chloro and trifluoromethyl group. It is a synthetic compound with potential antineoplastic and antibacterial properties. This chemical has been investigated for its potential in the treatment of cancer and infectious diseases. It has also demonstrated activity against a range of bacterial strains, making it a potential candidate for the development of new antibiotics. The compound's structure and properties make it suitable for further research and potential application in pharmaceutical and medical fields.

Upstream product

• 353258-31-8 8-chloro-6-(trifluoromethyl)imidazo[1,2,a]pyridine-2-carboxylic acid ethyl ester 
• 79456-26-1 2-amino-3-chloro-5-(trifluoromethyl)pyridine 

Downstream Products

• 1228376-14-4 8-chloro-2-(3-(2-chloro-4-nitrophenyl)-1,2,4-oxadiazol-5-yl)-6-(trifluoromethyl)-imidazo[1,2-a]pyridine 
• 1228375-18-5 ethyl 3-chloro-4-(5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazol-3-yl)benzoate 
• 1228375-30-1 3-(2-chloro-4-methoxyphenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole 
• 1228375-15-2 5-(8-chloro-6-(trifluoromethyl)imidazol[1,2-a]pyridine-2-yl)-3-(2,5-dichloro-4-methoxyphenyl)-1,2,4-oxadiazole 
• 1228375-36-7 3-(4-(allyloxy)-2,5-dichlorophenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole 
• 1228375-37-8 3-(4-(allyloxy)-2-chlorophenyl)-5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazole 
• 1228376-06-4 tert-butyl 3-(3-chloro-4-(5-(8-chloro-6-(trifluoromethyl)-imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazol-3-yl)phenyl)propanoate 
• 1228376-36-0 tert-butyl 3-(2,5-dichloro-4-(5-(8-chloro-6-(trifluoromethyl)-imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazol-3-yl)phenyl)propanoate 
• 1228376-43-9 8-chloro-2-[3-(2-chloro-5-fluoro-4-methoxy-phenyl)-[1,2,4]oxadiazol-5-yl]-6-trifluoromethyl-imidazo[1,2-a]pyridine 
• 1228375-42-5 tert-butyl 3-(5-chloro-4-(5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-yl)-1,3,4-oxadiazol-2-yl)-2-fluorophenyl)propanoate 
• 1228376-10-0 tert-butyl 3-(5-chloro-4-(5-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)-1,2,4-oxadiazol-3-yl)-2-fluorophenyl)propanoate 
• 1254304-22-7 8-chloro-N-[(2-chloro-5-methoxyphenyl)sulfonyl]-6-(trifluoromethyl)-imidazo[1,2-a]pyridine-2-carboxamide 
• 1254304-62-5 8-chloro-N-[(4-cyano-2,5-dimethylphenyl)sulfonyl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxamide 
• 1254306-69-8 8-chloro-N-[(2-chloro-5-ethylphenyl)sulfonyl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxamide 

Relevant articles and documents

Nitrogenous heterocyclic compound with nematocidal activity, preparation method and application thereof

The invention relates to a nitrogenous heterocyclic compound with nematocidal activity, a preparation method and application thereof. Specifically, the invention discloses a compound with a formula (I) or an optical isomer, cis-trans isomer or acceptable salt in agricultural pharmacology and a preparation method thereof. The invention further discloses an agricultural composition containing the compound and application thereof. The compound has excellent nematocidal activity.

HETERCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE

Described herein are heterocyclic compounds, compositions, and methods for their use for treatment of disease.

The discovery of fluazaindolizine: A new product for the control of plant parasitic nematodes

Fluazaindolizine is a new highly effective and selective product for the control of plant parasitic nematodes. Specificity for nematodes coupled with absence of activity against the target sites of commercial nematicides suggests that fluazaindolizine has a novel mode of action. The discovery, structure-activity development and biological properties for this new class of nematicides are presented.