353281-43-3

Basic information

• Product Name: dimethyl 4-{2-[6-(4-chlorobenzoyl)-2(3H)-benzothiazolon-3-yl]ethoxy}benzylidenemalonate
• Synonyms: dimethyl 4-{2-[6-(4-chlorobenzoyl)-2(3H)-benzothiazolon-3-yl]ethoxy}benzylidenemalonate
• CAS NO: 353281-43-3
• Molecular Weight: 552.004
• Mol File: 353281-43-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dimethyl 4-{2-[6-(4-chlorobenzoyl)-2(3H)-benzothiazolon-3-yl]ethoxy}benzylidenemalonate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 4-{2-[6-(4-chlorobenzoyl)-2(3H)-benzothiazolon-3-yl]ethoxy}benzylidenemalonate(353281-43-3)
• EPA Substance Registry System: dimethyl 4-{2-[6-(4-chlorobenzoyl)-2(3H)-benzothiazolon-3-yl]ethoxy}benzylidenemalonate(353281-43-3)

Safety Data

• Hazardous Substances Data: 353281-43-3(Hazardous Substances Data)

Upstream product

• 133044-33-4 6-(4-chlorobenzoyl)-2(3H)-benzothiazolone 

Downstream Products

• 353281-94-4 dimethyl 2-{4-[2-(6-(4-chlorobenzoyl)-2-oxo-1,3-benzothiazol-3(2H)-yl)ethoxy]-benzyl}malonate 

Relevant articles and documents

Novel 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles as PPARγ agonists

A series of 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles has been synthesized and tested for PPARγ agonist activity. SAR were developed and revealed that 6-acyl-2(3H)-benzothiazolone derivatives with 1,3-dicarbonyl group were the most potent. IP administration of compound 22 exhibited comparable levels of glucose and triglyceride correction to PO administration of rosiglitazone in the ob/ob mouse studies.